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IMPLEMENTASI HAK NARAPIDANA UNTUK MENDAPATKAN PENDIDIKAN (Tinjauan Pasal 9 Peraturan Pemerintah Nomor 32 Tahun 1999 Terkait Program Wajib Belajar 12 Tahun Study di Lembaga Pemasyarakatan Klas I Malang) [PDF]

open access: yes, 2009
Prisoners are lost people which their personality should be rebuild in order to fit them into community. Therefore it’s an obligation to study for 12 years for citizen and prisoners to increase education quality to lead the prisoners to a better way of ...
WICAKSONO, YUNIAR
core  

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

open access: yesMolecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Democracy and rule of law: the Hungarian goulash [PDF]

open access: yes, 2013
The article discusses the Tavares Report on the new constitutional changes in Hungary, the implications of the new Constitution on Hungary's obligation under the Treaty, on European Union, especially its continuing commitment to the Union founding ...
Ressel, James
core  

Political obligation

open access: yes, 2014
The moral obligation to obey the law, or as it is generally called, political obligation, is a moral requirement to obey the laws of one’s country. Traditionally, this has been viewed as a requirement of a certain kind, to obey the law because it is the law, as opposed to the content of particular laws.
openaire   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

SDC Supplier Obligation engagement project : process plan [PDF]

open access: yes, 2012
This process plan and timetable were used to form the basis of 'SDC Supplier Obligation project : household energy from 2011 : final report'.Publisher ...
Sustainable Development Commission
core  

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

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