FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
The influence of family instability on Mexican-origin adolescent delinquency through parental monitoring: Moderating roles of adolescent family obligation values and affiliation with deviant peers. [PDF]
Dev PsycholDu Y, Livas G, Wen W, Kim SY.
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
When Mania Outruns the Law: Managing Risk in the Liminal Zone. [PDF]
Can J PsychiatryCosta-Dookhan KA, Lustig A.
europepmc +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
What Makes Us React to the Abuse of Pets, Protected Animals, and Farm Animals: The Role of Attitudes, Norms, and Moral Obligation. [PDF]
Animals (Basel)Ruiz C, Vera A, Rosales C, Martín AM.
europepmc +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Addressing activities related to food supplements in European pharmacists' codes of ethics: textual analysis and proposals for ethical standards. [PDF]
BMC Med EthicsToma A, Crișan O.
europepmc +1 more source
Territorial Scope of Obligation to De-reference Based on the “Right to Be Forgotten”
Territorial Scope of Obligation to De-reference Based on the “Right to Be Forgotten”P(論文)
openaire
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source