Results 111 to 120 of about 1,388,590 (311)

The Hidden Effect of Rules: Behavioural consequences of Obligations [PDF]

open access: yes
How formal institutions (e.g. laws and public policies) affect human behaviour represents a crucial issue in economic analysis. Formal rules are defined as obligations backed by incentives. The economic literature has largely studied the role of material
Pietro Vertova, Roberto Galbiati
core  

Why Proximity Matters for the Concept of Supererogation [PDF]

open access: yes, 2017
The concept of supererogation is strictly correlated with duty, since its peculiar value is defined by acts that go beyond our regular obligations.
Grigoletto, Simone
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Admissibility of Compensation for Moral Harm as a Consequence of a Tort Committed During the Soviet Era

open access: yesТеоретическая и прикладная юриспруденция
The article substantiates the invalidity of the position formed in the Russian judicial practice about inadmissibility of compensation for physical and moral suffering caused to citizens as a result of offenses committed during the period of the Civil ...
S. S. Borja
doaj   +1 more source

Event Systems and Access Control [PDF]

open access: yes, 2006
We consider the interpretations of notions of access control (permissions, interdictions, obligations, and user rights) as run-time properties of information systems specified as event systems with fairness.
Merz, Stephan, Méry, Dominique
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Teacher and student psychological contract: a review of research

open access: yesВестник Мининского университета
Introduction. The article presents a theoretical analysis of the relationships that develop between participants in the educational process. The main idea is that teaching and upbringing are neither a one-sided, purposeful influence of a teacher on a ...
M. A. Gagarina
doaj   +1 more source

Competitively neutral universal service obligations [PDF]

open access: yes
Universal service obligations impose specific costs on the universal service provider. The measure of these costs and their financing have been studied along two complementary lines of reasoning: is the universal service obligation sustainable?
GAUTIER, Axel, WAUTHY, Xavier
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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