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Thermogenic defect in pre-obese ob/ob mice [PDF]
Nature, 1977 YOUNG genetically obese (ob/ob) mice develop obesity even when pair-fed to their lean littermates1–3. This is due to an unusually high metabolic efficiency, which we have suggested results from a reduction in the “maintenance increment” to the basal metabolic rate (BMR)4.
Trayhurn, P, Thurlby, P L, James, W P
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Longitudinal evaluation of hepatic lipid deposition and composition in ob/ob and ob/+ control mice
NMR in Biomedicine, 2013Obesity is associated with insulin resistance (IR) and hepatosteatosis. Understanding the link between IR and hepatosteatosis could be relevant to chronic clinical outcomes. The objective of this study was to quantitatively assess lipid deposition (fractional lipid mass, fLM) and composition (fraction of polyunsaturated lipids, fPUL and mean chain ...
Ye, Qiong +5 more
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To OBE Or Not To OBE: In Whose Best Interest?
Journal of Early Childhood Teacher Education, 1994(1994). To OBE Or Not To OBE: In Whose Best Interest? Journal of Early Childhood Teacher Education: Vol. 15, No. 2, pp. 5-23.
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Ob/ob mice as a model of delayed gastric emptying
Journal of Diabetes and its Complications, 2003Diabetic gastroparesis is a well-recognized delay of gastric emptying in diabetic patients. We assessed the gastric emptying rate in ob/ob mice, a genetic model of obesity and diabetes. The basal gastric emptying rate in 22- to 27-week-old ob/ob mice was significantly lower than that in 10- to 11-week-old ob/ob mice ...
Masaharu Uemoto +6 more
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, 2009
Gridded data sets derived through interpolation of station data have a number of potential inaccuracies and errors. These errors can be introduced either by the propagation of errors in the station data into derived gridded data or by limitations in the ...
N. Hofstra, M. Haylock, M. New, P. Jones
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Gridded data sets derived through interpolation of station data have a number of potential inaccuracies and errors. These errors can be introduced either by the propagation of errors in the station data into derived gridded data or by limitations in the ...
N. Hofstra, M. Haylock, M. New, P. Jones
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Temperature preference of genetically obese (ob/ob) mice
Physiology & Behavior, 1984Genetically obese (ob/ob) and lean mice selected their preferred ambient temperature in a thermal gradient. Preferred ambient temperature was defined as that ambient temperature which the mice selected for sleep during daylight hours. Lean mice selected a temperature of 31.2 degrees C which resulted in a body temperature (36.7 degrees C) not greatly ...
Harry J. Carlisle, Paul U. Dubuc
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Pancreatic Islets of Obese Hyperglycemic Mice (ob/ob)
Pancreas, 1992The development of the obesity-associated hyperglycemic syndrome in ob/ob mice, genetically determined, was observed over time by a combined functional and structural study of pancreatic islets. Islet areas increased with advancing age in ob/ob mice from 2 times at 1 month to 30 times at 6 months of age the size of lean mouse islets.
H.G. Pollock +3 more
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, 2012
1004 Background: Whole breast RT following conservation surgery (BCS) for low risk DCIS has remained controversial despite several large trials comparing RT to OBS, all showing significant benefit in local control with RT.
B. McCormick
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1004 Background: Whole breast RT following conservation surgery (BCS) for low risk DCIS has remained controversial despite several large trials comparing RT to OBS, all showing significant benefit in local control with RT.
B. McCormick
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, 2011
In order to investigate the deep crustal structure across the mid-northern continental margin of the South China Sea (SCS), a wide-angle OBS profile (OBS2006-3) was simulated by using forward and inversion methods. This profile, 319 km length and the NNW-
Xiao Wie +9 more
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In order to investigate the deep crustal structure across the mid-northern continental margin of the South China Sea (SCS), a wide-angle OBS profile (OBS2006-3) was simulated by using forward and inversion methods. This profile, 319 km length and the NNW-
Xiao Wie +9 more
semanticscholar +1 more source
Behavioral manipulation of the diabetic phenotype in ob/ob mice
Diabetes, 1984The genetically obese mouse (C57BL/6J ob/ob) is a commonly used model of non-insulin-dependent diabetes mellitus. However, our studies demonstrate that, while the animal is significantly hyperinsulinemic, it in fact does not show consistent hyperglycemia in the resting state.
Richard S. Surwit +4 more
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