Results 111 to 120 of about 495,030 (294)
Decoding anxiety: A scoping review of observable cues
Digital HealthBackground While anxiety disorders are one of the most prevalent mental diseases, they are often overlooked due to shortcomings of the existing diagnostic procedures, which predominantly rely on self-reporting.
Urška Smrke +4 more
doaj +1 more source
, 2008 . An edge-colored directed graph is observable if an agent that moves along its edges is able to determine his position in the graph after a sufficiently long observation of the edge colors. When the agent is able to determine his position only from time
Vincent, Raphaël Jungers, D. Blondel
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Linking cumulative carbon emissions to observable climate impacts
Environmental Research: ClimateAnthropogenic CO _2 emissions are causing climate change, and impacts of climate change are already affecting every region on Earth. The purpose of this review is to investigate climate impacts that can be linked quantitatively to cumulative CO _2 ...
Claude-Michel Nzotungicimpaye +1 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Nonthermal Ionization of Kilonova Ejecta: Observable Impacts
The Astrophysical JournalThe characteristic rapid rise and decline at optical wavelengths of a kilonova is the product of the low ejecta mass (≲0.05 M _⊙ ) and high ejecta velocity (≳0.1 c ). We show that, even at very early times (≲2 days), regions of ejecta fall below critical
D. Brethauer +3 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Hydrodynamic equations for microscopic phase densities
Open Physics, 2011 Gerasimenko Viktor +2 more
doaj +1 more source