Results 181 to 190 of about 764,924 (322)
Clinical significance of stratifying prostate cancer patients through specific circulating genes
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian+12 more
wiley +1 more source
A resilience assessment framework for slopes considering multiple performance indicators. [PDF]
Ju S, Jia J, Zhao Y, Xiang X, Tu B.
europepmc +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Tracing the inner edge of the habitable zone with sulfur chemistry. [PDF]
Jordan S, Shorttle O, Rimmer PB.
europepmc +1 more source
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
An Entropy Approach to Interdependent Human-Machine Teams. [PDF]
Lawless W, Moskowitz IS.
europepmc +1 more source
Observability of Decentralized Control Systems
Tsuneo Yoshikawa, Hiroaki Kobayashi
openalex +2 more sources
Observable quantities in cosmological models with strings [PDF]
Mariusz P. Dąbrowski, Jerzy Stelmach
openalex +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source