Results 231 to 240 of about 1,590,564 (275)

Parent-child agreement in reporting somatic distress, gastrointestinal symptoms, mental health, and general health in girls with functional abdominal pain. [PDF]

Eur J Pediatr
Duberg A, Eriksson M, Philipson A.
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

A Systematic Computational Framework for Practical Identifiability Analysis in Mathematical Models Arising from Biology. [PDF]

Adv Sci (Weinh)
Wang S, Hao W.
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Theoretical error modeling and analysis of strapdown inertial navigation system alignment under zero-velocity conditions. [PDF]

Sci Rep
Mohammadkarimi H, Mobtaker M, Alizadeh MH.   +2 more
europepmc   +1 more source

Low Risk Stocks Outperform within All Observable Markets of the World

, 2012
Nardin L. Baker, Robert A. Haugen
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Electrochemical CO₂ Capture, Release, and Reduction by a Benzothiadiazole Molecule with Multiple Redox States. [PDF]

ChemSusChem
Axelsson M, Torres-Mendez CE, Cheah MH, Tian H.   +3 more
europepmc   +1 more source

QUANTUM BOCHNER THEOREMS AND INCOMPATIBLE OBSERVABLES

, 2010
R. L. Hudson
openalex   +1 more source