Results 41 to 50 of about 764,924 (322)

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

Checking experiments with non-observable tree FSMs

open access: yesТруды Института системного программирования РАН, 2018
The paper addresses the problem of deriving preset checking experiments for non-observable FSMs. The fault model is considered to be a ‘white box’ where all possible implementations are explicitly enumerated.
N. . Kushik
doaj   +1 more source

Observable variations in human sex ratio at birth.

open access: yesPLoS Computational Biology, 2021
The human sex ratio at birth (SRB), defined as the ratio between the number of newborn boys to the total number of newborns, is typically slightly greater than 1/2 (more boys than girls) and tends to vary across different geographical regions and time ...
Yanan Long   +3 more
doaj   +1 more source

Towards Physics of Internal Observers: Exploring the Roles of External and Internal Observers [PDF]

open access: yesarXiv, 2023
In both quantum mechanics and relativity theory, the concept of the observer plays a critical role. However, there is no consensus on the definition of observer in these theories. Following Einstein's thought experiments, one could ask: What would it look like to sit inside a photon or to be a photon? And what type of observer could represent this more
arxiv  

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

open access: yesFEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka   +6 more
wiley   +1 more source

Observable Degree Analysis for Multi-Sensor Fusion System

open access: yesSensors, 2018
Multi-sensor fusion system has many advantages, such as reduce error and improve filtering accuracy. The observability of the system state is an important index to test the convergence accuracy and speed of the designed Kalman filter.
Zhentao Hu   +3 more
doaj   +1 more source

Bounds on right-handed neutrino parameters from observable leptogenesis

open access: yesJournal of High Energy Physics, 2022
We revisit the generation of a matter-antimatter asymmetry in the minimal extension of the Standard Model with two singlet heavy neutral leptons (HNL) that can explain neutrino masses. We derive an accurate analytical approximation to the solution of the
P. Hernández   +3 more
doaj   +1 more source

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Observer’s observables. Residual diffeomorphisms [PDF]

open access: yesClassical and Quantum Gravity, 2017
23 ...
Jedrzej Świeżewski   +2 more
openaire   +4 more sources

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

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