Results 81 to 90 of about 764,924 (322)

Using Rotations to Control Observable Relativistic Effects

open access: yesMathematics
This paper examines the possibility of controlling the outcome of measured (flat space-time) relativistic effects, such as time dilation or length contractions, using pure rotations and their nontrivial interactions with Lorentz boosts in the isometry ...
Danail Brezov
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Verdad como correspondencia con los hechos

open access: yesCrítica, 2018
The idea of truth as a correspondence between statements and facts which can be proved by observation, although intuitively plausiblebased on examples such as "this chalk is white"-, is vague-because the relation between statements and facts can be ...
Julián Garrido Garrido
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Flare Observations [PDF]

open access: yesLiving Reviews in Solar Physics, 2008
Living Reviews in Solar Physics, 14 (1)
openaire   +6 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Fault Diagnosis with Dynamic Observers [PDF]

open access: yesarXiv, 2010
In this paper, we review some recent results about the use of dynamic observers for fault diagnosis of discrete event systems. Fault diagnosis consists in synthesizing a diagnoser that observes a given plant and identifies faults in the plant as soon as possible after their occurrence.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

TMAC: a Transformer-based partially observable multi-agent communication method [PDF]

open access: yesPeerJ Computer Science
Effective communication plays a crucial role in coordinating the actions of multiple agents. Within the realm of multi-agent reinforcement learning, agents have the ability to share information with one another through communication channels, leading to ...
Xuesi Li   +3 more
doaj   +2 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

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