Management of the Clinically N0 Neck in Maxillary Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. [PDF]
Maglitto F +7 more
europepmc +1 more source
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Application effect of parental accompanying during anesthesia induction and recovery period nursing in endoscopic plasma-assisted tonsillectomy combined with adenoidectomy. [PDF]
Yang Y, He C, Qin J, Wu L.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
For your Silence and the Chaos therein
Abha Salwan
doaj
Two Weeks of Mirror Exposure Enhances Sensorimotor Cortex Activation but not Facial Mimicry in 4-Month-old Infants. [PDF]
Richmond C +3 more
europepmc +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Real-world Outcomes of Adjuvant Nivolumab in High-risk Bladder and Upper Tract Urothelial Carcinoma after Radical Surgery. [PDF]
Tazawa S +16 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Are Management Strategies Associated with Tolerance Acquisition in Infants with Cow's Milk-Induced Allergic Proctocolitis? [PDF]
Sefer AP +10 more
europepmc +1 more source

