Results 81 to 90 of about 2,693,151 (289)
Observational issues in loop quantum cosmology
, 2014 Quantum gravity is sometimes considered as a kind of metaphysical speculation. In this review, we show that, although still extremely difficult to reach, observational signatures can in fact be expected.
Barrau, A. +3 more
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Observational Features of Black Holes
, 2004 Recently considered a very attracting possibility to detect retro-MACHOs, i.e. retro-images of the Sun by a Schwarzschild black hole. In this paper we discuss glories (mirages) formed near rapidly rotating Kerr black hole horizons and propose a procedure
DePaolis, F. +3 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Clinical EpidemiologyChaplin AB, Archangelidi O, Hagberg KW, Neasham D, Kafatos G. Clin Epidemiol. 2025;17:1025—1038. https://doi.org/10.2147/CLEP.S558429 Following publication of the article, it has come to the authors attention that there are some errors in the
Chaplin AB +4 more
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Clinical EpidemiologyAnna B Chaplin,1 Olia Archangelidi,1 Katrina Wilcox Hagberg,2 David Neasham,1 George Kafatos1 1Center for Observational Research, Amgen Limited, Uxbridge, UK; 2Boston Collaborative Drug Surveillance Program, Lexington, MA, USACorrespondence: Anna B ...
Chaplin AB +4 more
doaj
Large-Scale Errors In CCD Photometry of M67
Open Astronomy, 2003 The accuracy of new CCD photometry in the Vilnius system of the M67 cluster is analyzed. The observational material is obtained during six observing runs in 1994-2001 with the 1 meter telescope of the USNO Flagstaff Station.
Laugalys V. +5 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source