Results 91 to 100 of about 689,003 (332)

Reconstructing the Primordial Spectrum with CMB Temperature and Polarization

, 2004
We develop a new method to reconstruct the power spectrum of primordial curvature perturbations, $P(k)$, by using both the temperature and polarization spectra of the cosmic microwave background (CMB).
A. A. Starobinsky, A. G. Polnarev, B. Kyae, C. R. Contaldi, E. Newman, G. B. Rybicki, H. Kodama, J. M. Cline, J. N. Goldberg, Jun’ichi Yokoyama, M. Liguori, M. Matsumiya, Misao Sasaki, Noriyuki Kogo, P. Mukherjee, Q. G. Huang, Q. G. Huang, S. Chandrasekhar, S. Hannestad   +18 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Error Cascades in Observational Learning: An Experiment on the Chinos Game [PDF]

The paper reports an experimental study based on a variant of the popular Chinos game, which is used as a simple but paradigmatic instance of observational learning.
Fernando Vega Redondo, Francesco Feri, Giovanni Ponti, Miguel A. Melendez-Jimenez   +3 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Summarizing multiple aspects of triple collocation analysis in a single diagram

Frontiers in Remote Sensing
With the ongoing expansion of global observation networks, it is expected that we shall routinely analyze records of geophysical variables such as temperature from multiple collocated instruments.
Leong Wai Siu, Xubin Zeng, Armin Sorooshian, Armin Sorooshian, Brian Cairns, Richard A. Ferrare, Johnathan W. Hair, Chris A. Hostetler, David Painemal, David Painemal, Joseph S. Schlosser, Joseph S. Schlosser   +11 more
doaj   +1 more source

Extreme Value laws for dynamical systems under observational noise

, 2014
In this paper we prove the existence of Extreme Value Laws for dynamical systems perturbed by instrument-like-error, also called observational noise.
Faranda, Davide, Vaienti, Sandro
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Numerical Studies on Forecast Error Correction of GRAPES Model with Variational Approach

Advances in Meteorology, 2019
To implement deterministic short-range numerical weather forecast error correction, this study develops a novel approach using the variational method and historical data.
Dengxin He, Zhimin Zhou, Zhaoping Kang, Lin Liu   +3 more
doaj   +1 more source