Results 141 to 150 of about 689,003 (332)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
How social is error observation? The neural mechanisms underlying the observation of human and machine errors [PDF]
, 2013 Charlotte Desmet +2 more
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The Recursive Form of Error Bounds for RFS State and Observation With <formula formulatype="inline"><tex Notation="TeX">$P_d < 1$</tex></formula> [PDF]
, 2013 Huisi Tong +3 more
openalex +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Modeling Solar Spectral Irradiance from Iron Lines Using the CODET Model Version 1.1
The Astrophysical JournalThe COronal DEnsity and Temperature (CODET) model is a physics-based model. This model uses the relationship between the magnetic field, density, temperature, and extreme ultraviolet (EUV) emission.
Jenny M. Rodríguez-Gómez
doaj +1 more source
Research on tidal harmonic analysis based on correlation observation error [PDF]
, 2020 Jin Zhang, Shujun Li, HaiGang Jiang
openalex +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Dynamic correction of forest fire spread prediction using observation error covariance matrix estimation technique based on FLC-GRU [PDF]
Tianyu Wu +5 more
openalex +3 more sources