Results 51 to 60 of about 689,003 (332)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Sensitivity Analysis for Multiple Comparisons in Matched Observational Studies through Quadratically Constrained Linear Programming

open access: yes, 2015
A sensitivity analysis in an observational study assesses the robustness of significant findings to unmeasured confounding. While sensitivity analyses in matched observational studies have been well addressed when there is a single outcome variable ...
Fogarty, Colin B., Small, Dylan S.
core   +2 more sources

On the White Dwarf distances to Galactic Globular Clusters [PDF]

open access: yes, 2001
We analyze in detail various possible sources of systematic errors on the distances of globular clusters derived by fitting a local template DA white dwarf sequence to the cluster counterpart (the so-called WD-fitting technique). We find that the unknown
Cassisi, S.   +4 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Pooled error variance and covariance estimation of sparse in situ soil moisture sensor measurements in agricultural fields in Flanders [PDF]

open access: yesSOIL
Accurately quantifying errors in soil moisture measurements from in situ sensors at fixed locations is essential for reliable state and parameter estimation in probabilistic soil hydrological modeling. This quantification becomes particularly challenging
M. G. A. Hendrickx   +11 more
doaj   +1 more source

Einstein's conversion from his static to an expanding universe

open access: yes, 2014
In 1917 Einstein initiated modern cosmology by postulating, based on general relativity, a homogeneous, static, spatially curved universe. To counteract gravitational contraction he introduced the cosmological constant.
Nussbaumer, Harry
core   +1 more source

Error analysis for stellar population synthesis as an inverse problem [PDF]

open access: yes, 2000
Stellar population synthesis can be approached as an inverse problem. The physical information is extracted from the observations through an inverse model. The process requires the transformation of the observational errors into model errors.
Moultaka, J., Pelat, D.
core   +3 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Time delay between images of the lensed quasar UM673

open access: yes, 2012
We study brightness variations in the double lensed quasar UM673 (Q0142-100) with the aim of measuring the time delay between its two images. In the paper we combine our previously published observational data of UM673 obtained during the 2003 - 2005 ...
A. S. Gusev   +53 more
core   +1 more source

Home - About - Disclaimer - Privacy