Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Targeted observations with an airborne wind lidar
This study investigates the possibilities and limitations of airborne Doppler lidar for adaptive observations over the Atlantic Ocean. For the first time, a scanning 2-µm Doppler lidar was applied for targeted measurements during the Atlantic The ...
Busen, Reinhold +4 more
core
Harvesting the Casualties of War: <i>Macrogerodonia peruviana</i> Rove Beetles Prey Exclusively Upon Wounded <i>Trigona</i> spp. Stingless Bees (Coleoptera: Staphylinidae; Hymenoptera: Apidae). [PDF]
Rivera E +4 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Cluster electron observations of the separatrix layer during traveling compression regions
[ 1] We present Cluster 4-point observations of electrons during traveling compression regions ( TCRs) on 19 September 2001. The electron and \B\ signatures vary with distance from the plasma sheet, confirming that transient plasma sheet bulges propagate
Fazakerley, AN +4 more
core
Graph Topology Reframes the Coherence of Cell-State Manifold Inference under Heterogeneous Single-Cell Observations. [PDF]
Tamura T +4 more
europepmc +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Multidisciplinary approach to reducing falls for people with dementia on an older adult mental health ward. [PDF]
Sorlie C +4 more
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Author Correction: Unexpected events and prosocial behavior: the Batman effect. [PDF]
Pagnini F +7 more
europepmc +1 more source

