Results 91 to 100 of about 13,153,558 (310)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
ShockABSTRACT Background: This study clarified the relationship between sex with survival and transfusion volume in severe trauma cases. Methods: A multicenter, collaborative post hoc analysis of patients with trauma in Japan was conducted. Patients aged ≥18 years with severe trauma indicated by an Injury Severity Score
Takumi, Tsuchida +5 more
openaire +3 more sources
Understanding the shape of the mixture failure rate (with engineering and demographic applications) [PDF]
Mixtures of distributions are usually effectively used for modeling heterogeneity. It is well known that mixtures of DFR distributions are always DFR. On the other hand, mixtures of IFR distributions can decrease, at least in some intervals of time.
Maxim S. Finkelstein
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Survival rate of gastric and esophageal cancers in Ardabil Province, North-West of Iran [PDF]
Background: Upper gastrointestinal cancer is the most common cancer in Ardabil Province, North-West of Iran, accounting for more than 50% of all cancer deaths in this area.
درخشان, محمدحسین +10 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Survival Analysis of Buccal Cancer and its Affecting Factors in a Medical Center of Central Taiwan
, 2009 [[abstract]]Background? Oral Cancer has been one of the top ten cancer diseases in Taiwan. It has become the fourth common cancer found especially in men. Moreover, the mortality rate of buccal cancer is rising higher yearly . Study objective?
FENG HEISH
core
Business Demography Dynamics in Portugal: A Non-Parametric Survival Analysis [PDF]
We address the post-entry performance of new Portuguese firms by investigating the structural characteristics of the hazard and survival functions, using non-parametric survival analysis.
Alcina Nunes, Elsa Sarmento
core +2 more sources
Integrated Multi-omics Survival Analysis of Gynecologic and Breast Cancers [PDF]
, 2023 openThis study utilized a multi-omics approach, incorporating gene expression, methylation, copy number variation, and mutation data, to analyze the survival of patients with Breast Carcinoma and Gynecologic Cancers (Ovarian Serous Cystadenocarcinoma ...
ZOLFAGHARI, AMIN
core
BMC GastroenterologyBackground The optimal clinical management of unresectable hepatocellular carcinoma (uHCC) is challenging for clinicians. Bayesian network meta-analysis was conducted to compare the efficacy and safety of different interventional strategies for uHCC ...
Xing-Yan Le +6 more
doaj +1 more source