Background High levels of serum lipopolysaccharide (LPS) were observed in sepsis patients with liver injury and high mortality. However, the role of liver in modulation LPS induced inflammatory injury was ill investigated.
Haoshu Fang +5 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Trends in milk production, calving rate and survival of cows in 14 Irish dairy herds as a result of the introgression of Holstein-Friesian genes [PDF]
peer-reviewedTrends in milk production, calving rates, and survival were monitored on a potential 5580 primiparous and multiparous Holstein-Friesian dairy cows across 14 Irish seasonal spring-calving dairy farms between the years 1990 and 2001. Over this
V. Ducrocq +13 more
core +1 more source
Effect of different levels of garlic alcoholic extract on the performance and survival of Rainbow trout (Oncorhyncus mykiss) [PDF]
In order to investigate the effects of alcoholic extract of garlic on the function and survival of rainbow trout 600 pieces of fish with an average weight of 15±5 g were randomly divided into four groups, each with three replicates.
s.j Mortazavi
doaj
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Survival according to BRAF-V600 tumor mutations--an analysis of 437 patients with primary melanoma.
The prognostic impact of BRAF-V600 tumor mutations in stage I/II melanoma patients has not yet been analyzed in detail. We investigated primary tumors of 437 patients diagnosed between 1989 and 2006 by Sanger sequencing.
Diana Meckbach +14 more
doaj +1 more source
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
Correcting Nesting-Success Estimates for Observer Effects: Maximum-Likelihood Estimates of Daily Survival Rates With Reduced Bias [PDF]
AbstractWe develop a statistical method that simultaneously estimates daily survival rate and observer effect. We used Monte Carlo simulation to (1) evaluate the performance of the model, (2) compare model performance with models that ignore observer effects, and (3) evaluate methods of choosing between competing models of survival.
Jay J. Rotellam +2 more
openaire +1 more source
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Oncological aid for colorectal cancer patients in Tomsk area: ways of cancer prevention
Aim of investigation. To estimate level of oncologic aid to patient with colorectal cancer in Tomsk area according to survival parameters.Material and methods.
L. D. Zhuykova +2 more
doaj

