Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Fractional CO<sub>2</sub> (FxCO<sub>2</sub>) Laser Therapy Combined with Erythromycin Ophthalmic Ointment-Based Moist Wound Healing for Facial Pigmented Scars: A Retrospective Observational Study. [PDF]
Jin Y, Jin Q, Zhi J, Zheng Z, Jin C.
europepmc +1 more source
Functional Markers of Vascular Aging: Subendocardial Viability Ratio, Augmentation Pressure, and Augmentation Index as Links to Atherosclerotic Cardiovascular Disease Risk. [PDF]
Yang L +9 more
europepmc +1 more source
From Robust Control to Cyber-Resilience: A Comprehensive Overview of the Polytopic Framework for Safety-Critical Systems. [PDF]
Rebai SB.
europepmc +1 more source
Sliding Mode Observer with Exponential Reaching Law for Speed Estimation of a Six-Phase Induction Machine. [PDF]
Delorme L +6 more
europepmc +1 more source
Study Design, Reconstructive Modalities, and Patient-Reported Outcome Documentation in a Curated Corpus of Facial Basal Cell Carcinoma Reconstruction Studies: An Exploratory Meta-Research Analysis. [PDF]
Adam II +10 more
europepmc +1 more source
Evaluator standpoint and ecological context shape psychological momentum measurement in sport. [PDF]
Asai Y, Kida N.
europepmc +1 more source
Asymptotic convergence unknown input observer design via interval observer
Automatica, 2023Thach Ngoc Dinh, Yuhang Fu
exaly
Second-order sliding-mode observer for mechanical systems
IEEE Transactions on Automatic Control, 2005Arie Levant +2 more
exaly
Disturbance Observer-Based Robust Control and Its Applications: 35th Anniversary Overview
IEEE Transactions on Industrial Electronics, 2020Kouhei Ohnishi +2 more
exaly

