Results 171 to 180 of about 100,465 (216)

Reproducibility of fetal global longitudinal strain measured with speckle tracking echocardiography using a fixed cardiac cycle. [PDF]

PLoS One
Meireson E, de Vet C, van Laar JOEH, Mussche P, Roelens K, van Oostrum NHM.   +5 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The AI Innerve Algorithm: Automatic Reproducible Reading for Intraepidermal Nerve Fiber Density Analysis, a New Tool for Small-Fiber Neuropathy Diagnosis. [PDF]

Eur J Neurol
Labeyrie C, Lorenzo de Brionne A, Trassard O, Blot V, Petit O, Hervault D, Medernach D, Morassi O, Guettier C, Adams D, Brunel N, Adam C.   +11 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Diagnostic performance of the expanded National Institutes of Health Stroke Scale for the assessment of anterior and posterior circulation strokes. [PDF]

Front Neurol
Forlivesi S, Balbarini A, Bigliardi G, D'Amico R, Rosafio F, Vandelli L, Dell'Acqua ML, Casoni F, Meletti S, Cavazzuti M, Zini A.   +10 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Masmali and Rolando Scales in Distinct Brachycephalic Dogs: Healthy or Unhealthy Tears? [PDF]

Vet Ophthalmol
da Silva PHS, Castanheira ITF, Campos LRS, Galera PD.   +3 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Clinical tools to differentiate behavioral variant frontotemporal dementia from phenocopies. [PDF]

Alzheimers Dement (Amst)
Flavell J, Lee S, McElligott CAT, Coleman FM, Fazlollahi A, McCann EG, Nguyen DD, Nestor PJ.   +7 more
europepmc   +1 more source