Results 201 to 210 of about 94,612 (266)

Learned foveal representations, not gaze-mediated information access, underlie perceptual advantages for canonical face configurations. [PDF]

J Vis
Chakravarthula PN, Tsank Y, Eckstein MP.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Pilot CBCT-Based Volumetric and Morphometric Analysis of the Pterygopalatine Fossa in a Romanian Cohort: A Retrospective Study. [PDF]

Diagnostics (Basel)
Kui A, Buduru S, Labunet A, Iacob S, Iacob EA, Petruțiu AS, Popa D, Ile IV, Negucioiu M.   +8 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Preset-time control of UGV swarms with multiplicative noise and RISE disturbance observer. [PDF]

Sci Rep
Pang H, Yu J, Li S, Zhang Z, Zhou F, Li Y.   +5 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Intra- and inter-observer reliability of ultrasound muscle thickness of gluteal and biceps femoris long head in individuals with and without SCI. [PDF]

Clin Physiol Funct Imaging
Wijker BJ, de Groot S, Denneman B, Brouwer P, Tomaras V, Haarler A, Weide G, Mokkink LB, van Dongen JM, Janssen TWJ.   +9 more
europepmc   +1 more source

On the usefulness of Thompson´s test with a four-point scale after Achilles tendon rupture, a pilot study. [PDF]

BMC Musculoskelet Disord
Wetterteg AL, Riad J, Nordin P.
europepmc   +1 more source

Blinded, bias-controlled multi-rater evaluation of human-versus-AI brain metastasis segmentation using a hybrid foundation-model framework. [PDF]

Med Phys
Han Y, Zhu E, Mekdash MHA, Awad O, Pathak P, Liang S, Hamstra DA, Zhang X, Siddiqui ZA, Sun B.   +9 more
europepmc   +1 more source

Uncertainty-Aware Framework for CT Radiation Dose Optimization in the Active Surveillance of Small Renal Masses: Clinical and Radiological Considerations. [PDF]

Diagnostics (Basel)
Elsabagh MA, Samy Talaat A, Elwi D, Hassan SM, Alqassimi S, Hassan E.   +5 more
europepmc   +1 more source