Results 61 to 70 of about 253,330 (372)
Advanced Science, EarlyView.We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich +8 more
wiley +1 more source
Prevalence of obsessive compulsive symptoms among patients with schizophrenia
Industrial Psychiatry Journal, 2009 Background: Obsessive compulsive symptoms in schizophrenia are well recognized but are a less-researched entity. These symptoms have important implications for management and prognosis.
Smita Hemrom +5 more
doaj +1 more source
Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]
, 2006 Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P +8 more
core +1 more source
Advanced Intelligent Systems, EarlyView.This study, utilizing two large‐cohort datasets, employs interpretable neural networks. It demonstrates that incorporating brain morphology and functional and structural networks enhances predictive accuracy for general psychopathology and its dimensions.
Jing Xia, Nanguang Chen, Anqi Qiu
wiley +1 more source
Brain Sciences, 2023 Symptoms of obsessive–compulsive disorder are related to atypical sensory processing, particularly sensory over-responsivity, in both children and adults.
Ilil Tal +3 more
doaj +1 more source
Journal of Psychiatry & Neuroscience, 2018 BACKGROUND Recently, a new thermal lesioning approach using magnetic-resonance-guided focused ultrasound (MRgFUS) was introduced for the treatment of neurologic disorders. However, only 2 studies have used this approach for treatment-refractory obsessive-
Se Joo Kim +5 more
semanticscholar +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Natural History Studies can help inform clinician and caregiver expectations, form the basis of management guidelines, and provide a comparator for therapeutic intervention. In rare conditions, where collection of prospective longitudinal data is untimely and impractical, quasi‐natural history data—from multiple individuals of different ages ...
E. Woods +16 more
wiley +1 more source
Diagnosis of obsessive-compulsive disorder in the course of bipolar disorder
Psychiatria i Psychologia Kliniczna, 2016 Aim: The aim of this study was to evaluate the coexistence of obsessive-compulsive symptoms with bipolar disorder (during the manic phase, depressive phase and remission).
Maciej Żerdziński
doaj +1 more source
A Five-Factor Measure of Obsessive-Compulsive Personality Traits. [PDF]
, 2012 The current study provides convergent, discriminant, and incremental validity data for the Five-Factor Obsessive-Compulsive Inventory (FFOCI), a newly-developed measure of traits relevant to obsessive-compulsive personality disorder (OCPD) from the ...
Lynam, Donald R +4 more
core +3 more sources
On the Nature of Obsessions and Compulsions [PDF]
, 2013 In this chapter, we give an overview of current and historical conceptions of the nature of obsessions and compulsions. We discuss some open questions pertaining to the primacy of the affective, volitional or affective nature of obsessive-compulsive disorder. Furthermore, we add some phenomenological suggestions of our own.
Sanneke de Haan +2 more
openaire +3 more sources