Results 141 to 150 of about 508,157 (387)

Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes [PDF]

open access: yes, 2017
Objective: There remains controversy over how women with abnormal thyroid function tests in pregnancy should be classified. In this study we assessed the proportion of women with thyroid stimulating hormone (TSH) ≥ 2.5 mU/l in a large obstetric cohort,
Carty, David M.   +4 more
core   +1 more source

Obesity and gynaecological and obstetric conditions: umbrella review of the literature

open access: yesBritish medical journal, 2017
Objective To study the strength and validity of associations between adiposity and risk of any type of obstetric or gynaecological conditions. Design An umbrella review of meta-analyses.
I. Kalliala   +10 more
semanticscholar   +1 more source

Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies

open access: yesAdvanced Science, EarlyView.
Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren   +7 more
wiley   +1 more source

Chlamydia trachomatis and the risk of spontaneous preterm birth, babies who are born small for gestational age, and stillbirth: A population-based cohort study [PDF]

open access: yes, 2018
Background: Chlamydia trachomatis is one of the most commonly diagnosed sexually transmitted infections worldwide, but reports in the medical literature of an association between genital chlamydia infection and adverse obstetric outcomes are inconsistent.
Donovan, Basil   +7 more
core   +1 more source

Effect of Rhesus D incompatibility on schizophrenia depends on offspring sex. [PDF]

open access: yes, 2008
Rhesus D incompatibility increases risk for schizophrenia, with some evidence that risk is limited to male offspring. The purpose of this study is to determine whether risk for schizophrenia due to Rhesus D incompatibility differs by offspring sex using ...
Hsieh, Hsin-Ju   +7 more
core   +1 more source

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu   +10 more
wiley   +1 more source

Nurses\u27 Own Birth Experiences Influence Labor Support Attitudes and Behaviors [PDF]

open access: yes, 2016
Objective To describe the attitudes of intrapartum nurses about the importance of and intent to provide professional labor support (PLS); barriers to PLS, such as perceived subjective norms and perceived behavioral control; and relationships among ...
Aschenbrenner, Ann P.   +3 more
core   +1 more source

The effectiveness of mHealth interventions for maternal, newborn and child health in low- and middle-income countries:Protocol for a systematic review and meta-analysis [PDF]

open access: yes, 2014
Rates of maternal, newborn and child (MNCH) mortality and morbidity are vastly greater in low– than in high–income countries and represent a major source of global health inequity.
Begg   +18 more
core   +6 more sources

Hydrolyzable Bio‐Based Bisphenols Enabled by the Tishchenko Reaction for Polyurethane Vitrimers with Closed‐Loop Recyclability

open access: yesAdvanced Science, EarlyView.
This study employs the Tishchenko coupling reaction to obtain bio‐based bisphenols containing degradable ester bonds with 100% atom utilization. Based on these bio‐based bisphenols, a fully bio‐based polyurethane Covalent Adaptable Networks are constructed, while simultaneously endowing the material with closed‐loop recyclability, degradability, and ...
Jiewen Wang   +7 more
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

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