Results 151 to 160 of about 348,423 (344)
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai +15 more
wiley +1 more source
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao +8 more
wiley +1 more source
Kristabella Gianina,1 Anita Rachmawati,1 Bogie Prabowo Rahmarjanto,2 Gayuh Tunggal Rachmadhini2 1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – RSUP Dr. Hasan Sadikin, Bandung, Indonesia; 2Department of Obstetrics
Gianina K +3 more
doaj
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai +12 more
wiley +1 more source
[Obstetric Antiphospholipid Syndrome: Insights on the Diagnosis, Treatment, and Hot Issues]. [PDF]
Rui Gao, Lang Qin
openalex +1 more source
Pregnancy complications and obstetric care in women with inherited bleeding disorders [PDF]
Rezan A. Kadir +7 more
openalex +1 more source
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing +14 more
wiley +1 more source
Utilization of obstetric ultrasonography and findings in a cottage hospital in Nigeria
Grace Ben Inah +5 more
openalex +2 more sources
This study introduces a biomarker‐agnostic diagnostic strategy for ovarian cancer, utilizing a machine learning‐enhanced electronic nose to analyze volatile organic compound signatures from blood plasma. By overcoming the dependence on specific biomarkers, this approach enables accurate detection, staging, and cancer type differentiation, offering a ...
Ivan Shtepliuk +4 more
wiley +1 more source

