Results 151 to 160 of about 348,423 (344)

Guidelines of the Polish Society of Gynecologists and Obstetricians on the obstetric care of women with obesity

open access: gold, 2023
Dorota Bomba‐Opoń   +7 more
openalex   +2 more sources

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

open access: yesAdvanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai   +15 more
wiley   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

open access: yesAdvanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao   +8 more
wiley   +1 more source

Difficult Diagnosis and Management of a Torsion-Associated Giant Paratubal Serous Borderline Mass: Unraveling a Rare Gynecologic Pathology—A Case Report

open access: yesInternational Journal of Women's Health
Kristabella Gianina,1 Anita Rachmawati,1 Bogie Prabowo Rahmarjanto,2 Gayuh Tunggal Rachmadhini2 1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – RSUP Dr. Hasan Sadikin, Bandung, Indonesia; 2Department of Obstetrics
Gianina K   +3 more
doaj  

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai   +12 more
wiley   +1 more source

Pregnancy complications and obstetric care in women with inherited bleeding disorders [PDF]

open access: bronze, 2013
Rezan A. Kadir   +7 more
openalex   +1 more source

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing   +14 more
wiley   +1 more source

Utilization of obstetric ultrasonography and findings in a cottage hospital in Nigeria

open access: hybrid, 2021
Grace Ben Inah   +5 more
openalex   +2 more sources

Biomarker‐Agnostic Detection of Ovarian Cancer from Blood Plasma Using a Machine Learning‐Driven Electronic Nose

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces a biomarker‐agnostic diagnostic strategy for ovarian cancer, utilizing a machine learning‐enhanced electronic nose to analyze volatile organic compound signatures from blood plasma. By overcoming the dependence on specific biomarkers, this approach enables accurate detection, staging, and cancer type differentiation, offering a ...
Ivan Shtepliuk   +4 more
wiley   +1 more source

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