Results 41 to 50 of about 5,560 (192)

Outcome of urethral reconstruction among vesico-vaginal fistula patients: a cross-sectional study

African Journal of Urology, 2021
Background Obstetric fistula (OF) complicated by urethral loss (UL) poses a challenge to both the fistula surgeon and obstetric fistula patient. The involvement of the urethra and urethral closure mechanism in OF is an important determinant of successful
Olatunji O. Lawal, Rukiyat Adeola Abdus-salam, Oluwasomidoyin O. Bello, Imran O. Morhason-Bello, Oladosu A. Ojengbede   +4 more
doaj   +1 more source

Facilitating Genetic Testing for Perinatal Demise: Development of a Multidisciplinary Workflow

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic contributors to perinatal demise are common but frequently undiagnosed due to clinical and logistical barriers. We aimed to improve access to genetic for intrauterine fetal demise (IUFD), stillbirth, and early neonatal death by developing a multidisciplinary workflow.
Mackenzie Mosera, Samantha Stover, Elise Boos, Molly Casey, Joseph Fanning, Chelsea Fechter, Matthew Grace, L. Dupree Hatch, Michaela Ibach, Carla Jackson, Jiancong Liang, Caitlin Mann, Emily A. Morris, Jessica Turnbull, Marie Williams, Bryce A. Schuler   +15 more
wiley   +1 more source

Low‐intervention clinical trials in Spain: Do they progress?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza, Mayro J. Cortés Pestana, Kristopher Amaro, Rosa M. Antonijoan, Caridad Pontes   +4 more
wiley   +1 more source

The prevalence and management of obstetric fistula among women of reproductive age in a low-resource setting

Healthcare in Low-resource Settings, 2023
Obstetric fistula is one of the most significant obstetrical concerns and apparent indications of maternal morbidity in low-resource nations. Therefore, the study assessed the prevalence and management of fistula among women of reproductive age (15-49 ...
Olaniyi Felix Sanni, Michael Olugbamila Dada, Abimbola Oluseyi Ariyo , Aisha Oluwakemi Salami , Olaide Lateef Afelumo , Oluwasola Stephen Ayosanmi , Olaiya Paul Abiodun , Elizabeth Abike Sanni   +7 more
doaj   +1 more source

Pharmacokinetics, safety, tolerability and fluorescence imaging of nizaracianine triflutate administered in three divided doses to healthy volunteers

British Journal of Clinical Pharmacology, EarlyView.
Aim Fluorescence‐guided surgery enhances intraoperative visualization of anatomical structures. Nizaracianine is a near‐infrared fluorescent agent that is exclusively renally cleared in animal models. It enables real‐time ureteral imaging and identification, potentially reduces risk of injury and facilitates assessment before surgical closure.
Lisanne K. A. Neijenhuis, Cedric M. W. Pesch, John V. Frangioni, Alexander L. Vahrmeijer, Jacobus Burggraaf, Naomi B. Klarenbeek   +5 more
wiley   +1 more source

Exploring awareness of obstetric fistula in Eastern and Northern Nigeria: perceived causes, symptoms, and availability of treatment services

Global Health Research and Policy, 2022
Background Evidence suggests that there are approximately two female genital fistula cases per 1000 women of reproductive age in sub-Saharan Africa.
Emmanuel Kelechi Nwala, Charles Nwaigwe, Pooja Sripad, Charlotte E. Warren, Salisu Ishaku, Solomon Kongyamba   +5 more
doaj   +1 more source

Maternal morbidity following a trial of labor after cesarean birth: A scoping review of operative vaginal birth compared with cesarean birth in the second stage of labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Increased use of operative vaginal birth (OVB; forceps and vacuum) has been proposed as a strategy to avoid cesarean birth (CB) among individuals who elect a trial of labour after CB (TOLAC). The relative maternal safety of OVB and CB in individuals with a TOLAC is poorly understood. Objective To summarize the available evidence and
Irina I. Oltean, Vanessa Hébert, Giulia M. Muraca   +2 more
wiley   +1 more source

Urethral injury during vaginal delivery: Incidence, management and long‐term outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines the incidence, obstetric risk factors, surgical management, and long‐term outcomes of obstetric‐associated urethral injuries during vaginal deliveries. Methods A retrospective case series was conducted at a single, tertiary university‐affiliated medical center between January 2018 and December 2023.
Yoav Baruch, Ronen Gold, Yariv Stabholz, Michael Lavie, Yariv Yogev, Asnat Groutz   +5 more
wiley   +1 more source

A comparison of quality of life of obstetric fistula survivors in Zimbabwe before and after surgical treatment

African Journal of Urology, 2021
Background In Zimbabwe, repair of obstetric fistula was established as a public health intervention in 2015. The aim of this study was to assess the quality life of obstetric fistula survivors before and after surgical repair of the fistula.
Chipo Chimamise, Iris Shiripinda, Stephen P. Munjanja, Mazvita Machinga   +3 more
doaj   +1 more source

Non‐Nutritive Artificial Sweeteners Aspartame and Acesulfame‐K Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease in Male Ldlr−/− Mice

iNew Medicine, EarlyView.
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu, Xiaohua Jiang, Jianping Weng, Suowen Xu   +3 more
wiley   +1 more source