Results 101 to 110 of about 635,507 (332)

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Challenges of anesthesiology in non-obstetric surgical procedures during the gestational period

open access: yes, 2022
As intervenções cirúrgicas não obstétricas em gestantes apesar de terem baixa incidência, acontecem, e necessitam de maiores estudos quanto ao manejo anestesiológico, devido a gestação ser um período marcado por alterações fisiológicas, hormonais e anatômicas para as mães, e de grande diferenciação celular e crescimento para os embriões e/ou fetos, o ...
Freitas, Jefferson Alves   +2 more
openaire   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

Obstetric Nurses’ Perceived Barriers to Immediate Skin to Skin Contact after Cesarean Birth [PDF]

open access: yes, 2018
Despite the strong evidence supporting immediate skin to skin contact (SSC) after birth, research suggests that patients who undergo cesarean births do not have the same opportunities for SSC as patients who undergo vaginal births.
Balatero, Joelene Sarmiento
core   +1 more source

The incidence of surgical glove perforation during obstetric and gynaecological surgical procedures.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1992
The increasing prevalence of diseases such as AIDS and hepatitis B makes safe surgical techniques more important than ever before. Intact surgical gloves act as a barrier against these infections and a study was therefore done to determine the incidence of surgical glove perforation during obstetric and gynaecological surgical procedures.
J T, Nel   +4 more
openaire   +1 more source

Incisional surgical site infections in obstetric and gynecological procedures in a tertiary care hospital in Northern India

open access: yesInternational Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2020
Background: To find the incidence of incisional surgical site infection (ISSI) in obstetric and gynecological procedures, the risk factors, the microbial spectrum, the antibiotic sensitivity and the impact on the hospital stay. Methods: A prospective observational study was done under the department of obstetrics and gynecology, Era’s Lucknow medical ...
Savita Chandra, Shodashi Saxena
openaire   +2 more sources

Factors related to surgical site infections after obstetric procedures [Abstract in English]

open access: yes, 2013
AIMS: Surgical site infection is the second main cause of nosocomial infections and a major complication during postpartum period. This study aimed to describe characteristics and risk factors found in puerperal women who had surgical site infection ...
C. Petter   +3 more
semanticscholar   +1 more source

A Single‐Enzyme Activated CRISPR‐Cas12a Nano System via Subtly Balanced dsDNA for Kinetic‐Gated UDG Detection and Spatiotemporal Cellular Imaging

open access: yesAdvanced Science, EarlyView.
Kinetic‐gated CRISPR–Cas12a activation enables single‐enzyme detection and spatiotemporal imaging of UDG ABSTRACT Uracil‐DNA glycosylase (UDG) is a key enzyme in base excision repair and an important biomarker for genomic stability and disease. In many reported sensing systems, uracil excision is coupled to signal generation through additional ...
Kejun Dong   +12 more
wiley   +1 more source

Oral transmucosal fentanyl [PDF]

open access: yes, 1998
None ...
D. Prosser   +4 more
core   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li   +10 more
wiley   +1 more source

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