Results 171 to 180 of about 703,365 (264)

Suicide and Self‐Harm in Intellectual Disability: A Systematic Review and Meta‐Analysis

open access: yesJournal of Intellectual Disability Research, Volume 70, Issue 4, Page 364-374, April 2026.
ABSTRACT Background Individuals with intellectual disabilities (ID) are disproportionately exposed to several risk factors for suicidality. However, no meta‐analysis has yet quantified the relative risk of suicide and self‐harm, including suicide attempts, within this population. The aim of this project was to bring together and synthesise the research
Sara Lindstedt   +8 more
wiley   +1 more source

The impact of the patient macroenvironment on molecular subgroups in endometrial cancer

open access: yesCancer, Volume 132, Issue 6, 15 March 2026.
Abstract More than half of endometrial cancer diagnoses can be attributed to obesity. A purely molecular classification in endometrial cancer hampers further understanding of the impact of patient macroenvironment as a major risk factor. The relationship between patient factors, such as age, body mass index (BMI), comorbidity, and ethnicity, and ...
Henrica M. J. Werner   +14 more
wiley   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, Volume 20, Issue 3, Page 709-726, March 2026.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

open access: yesAdvanced Materials, Volume 38, Issue 14, 6 March 2026.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas   +7 more
wiley   +1 more source

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