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Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells
Advanced Science, EarlyView.Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang +20 more
wiley +1 more source
Cancer Cytopathology, Volume 130, Issue 12, Page 939-948, December 2022., 2022 Background High‐risk human papilloma virus (HR HPV) testing and liquid‐based cytology are used for primary cervical screening. Digital cytology, based on whole‐slide scanned samples, is a promising technique for teaching and diagnostic purposes. The aim of our study was to evaluate the interobserver and intraobserver variation in low‐grade squamous ...
Ivana Kholová +18 more
wiley +1 more source
Holistic obstetrics: the origins of "natural childbirth" in Britain.
, 2003 The term "natural childbirth" denotes an approach to childbirth characterised by a bias towards physical and mental hygiene in the management of pregnancy and labour.
Moscucci, O
core +2 more sources
High-fidelity simulation increases obstetric self-assurance and skills in undergraduate medical students [PDF]
, 2012 Objective: Teaching intrapartum care is one of the most challenging tasks in undergraduate medical education. High-fidelity obstetric simulators might support students' learning experience.
Fischer, Martin R. +5 more
core +1 more source
Evidence for uteroplacental malperfusion in fetuses with major congenital heart defects. [PDF]
, 2020 AIMS: Fetuses affected by congenital heart defects (CHD) are considered to be at increased risk of fetal growth restriction and intrauterine demise.
Binder, J +5 more
core +2 more sources
Artificial Intelligence in Obstetrics and Gynaecology: Is This the Way Forward?
In Vivo, 2019 An increasing trend in funding towards artificial intelligence (AI) research in medicine has re-animated huge expectations for future applications. Obstetrics and gynaecology remain highly litigious specialities, accounting for a large proportion of ...
E. Emin +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong +13 more
wiley +1 more source
Anaesthesia, 2015 The Obstetric Anaesthetists' Association and Difficult Airway Society have developed the first national obstetric guidelines for the safe management of difficult and failed tracheal intubation during general anaesthesia. They comprise four algorithms and
M. Mushambi +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li +19 more
wiley +1 more source
Cytometry Part A, Volume 101, Issue 12, Page 1057-1067, December 2022., 2022 Abstract Cell loss during detection and isolation of circulating tumor cells (CTCs) is a challenge especially when label‐free pre‐enrichment technologies are used without the aid of magnetic particles. Although microfluidic systems can remove the majority of “contaminating” white blood cells (WBCs), their remaining numbers are still impeding single CTC
Liwen Yang +10 more
wiley +1 more source