Results 121 to 130 of about 843,641 (407)

Potentiating the Efficacy of mRNA Vaccines through NIR‐II Imaging‐Guided Precise Vaccination

Advanced Science, EarlyView.
A supramolecular strategy is utilized to integrate IR780‐C16 lipids into conventional LNPs, pioneering a novel NIR‐II‐LNPs platform that elucidates the correlations between mRNA vaccines efficacy and vaccination parameters in a non‐invasive approach.
Mengfei Li, Xue Zheng, Xinyang Yu, Shaolong Qi, Shoujun Zhu, Guocan Yu, Songling Zhang   +6 more
wiley   +1 more source

Normal birth in Kazakhstan: Labor management practice in accordance with World Health Organization's recommendations

Journal of Research in Medical Sciences, 2016
Background: Over the last 10 years, the evidential practice has been developing in Kazakhstan. The clinical protocols of diagnostics and treatment were implemented in the country since 2007. We analyzed the normal birth practice in Kazakhstan.
Aizhan D Kyzayeva, Aigul B Kudamanova
doaj   +1 more source

Minding the Shop: The Case of Obstetrics Conferences [PDF]

We estimate the impact of annual obstetricians and gynecologists’ conferences on births in Australia and the United States. In both countries, the number of births drops by 1 to 4 percent during the days on which these conferences are held. We argue that
Andrew Leigh, Elena Varganova, Joshua S. Gans   +2 more
core  

Assessment of Risk Factors of Septic Complications of the Puerperium [PDF]

, 2018
Postpartum purulent-septic complications (PPSC) and their problems are most urgent for modern obstetrics due to their significant frequency. Maternal sepsis is one of the leading causes of maternal mortality around the world, accounting for about one ...
Feyta, Y. (Yuliya), Pyrohova, V. (Vira)
core   +2 more sources

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

FIGO's updated recommendations for misoprostol used alone in gynecology and obstetrics

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2017
1International Federation of Gynecology and Obstetrics, London, UK 2Gynuity Health Projects, New York, NY, USA 3Department of Women’s and Children’s Health, University of Liverpool, Liverpool, UK 4Department of Obstetrics and Gynecology, University of ...
Jessica L. Morris, B. Winikoff, R. Dabash, A. Weeks, A. Faúndes, K. Gemzell‐Danielsson, N. Kapp, L. Castleman, Caron R Kim, P. Ho, G. Visser   +10 more
semanticscholar   +1 more source

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

Identification of Key Mitochondrial Autophagy-Related Genes in Fetal Growth Restriction

International Journal of Women's Health
Yanru Yao, Gang Lei, Guangxin Pan, Guoping Xiong, Jian Shen Obstetric, Centre Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, Hubei, 430014, People’s Republic of ChinaCorrespondence: Guoping Xiong, Obstetric, Centre Hospital of ...
Yao Y, Lei G, Pan G, Xiong G, Shen J
doaj  

Bleeding changes after levonorgestrel 52-mg intrauterine system insertion for contraception in women with self-reported heavy menstrual bleeding. [PDF]

, 2020
BackgroundThe levonorgestrel 52-mg intrauterine system has proven efficacy for heavy menstrual bleeding treatment in clinical trials, but few data exist to demonstrate how rapidly the effects occur and the effects in women with self-reported heavy ...
Chen, Beatrice A, Creinin, Mitchell D, Eisenberg, David L, Olariu, Andrea I, Schreiber, Courtney A, Turok, David K   +5 more
core  

Scaffolding Protein ENH Promotes Tumor Angiogenesis and Growth Through Macrophage Recruitment and Polarization

Advanced Science, EarlyView.
In tumor cells, ENH prompts the interaction between YAP and KPNA2. This interaction enables YAP to translocate into the nucleus, where it enhances the transcription of CCL5. Consequently, this up‐regulation of CCL5 drives the infiltration of tumor‐associated macrophages (TAMs) and their polarization toward the M2 phenotype, ultimately facilitating ...
Yueli Shi, Zhiyong Xu, Huan Wang, Bufu Tang, Nueraili Maihemuti, Xinyuan Jiang, Xiuying Chen, Mingshu Xiao, Sujing Jiang, Yun Xu, Peng Xiao, Jiangnan Zhao, Kaiyue Zhang, Mengshu Li, Kai Wang   +14 more
wiley   +1 more source