Results 141 to 150 of about 843,641 (407)

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang   +18 more
wiley   +1 more source

Clean Cut (adaptive, multimodal surgical infection prevention programme) for low‐resource settings: a prospective quality improvement study

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester   +16 more
wiley   +1 more source

Bibliometric Analysis On Laparoscopic Hysterectomy Technique in Obstetrics And Gynecology Research Area

open access: yesJournal of Contemporary Medicine, 2023
Background/Aim: This bibliometric study aimed to analyze published articles in the field of laparoscopic hysterectomy in order to identify their characteristics and trends.
Fatmahorasan Altıntaşoğlu
doaj  

Prenatal Corticosteroids for Reducing Morbidity and mortality after Preterm Birth [PDF]

open access: yes, 2005
Annotated and edited transcript of a Witness Seminar held on 15 June 2004. Introduction by Barbara Stocking, Oxfam. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2005.©The Trustee of the Wellcome Trust, London, 2005.All
REYNOLDS, LA, Tansey, EM
core  

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu   +17 more
wiley   +1 more source

Evaluating the Correlation of Systemic Inflammatory Response Syndrome with Mortality and Morbidity in Critically Ill Obstetric Patients in ICU

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2010
Background and Objectives: Systemic inflammatory response syndrome (SIRS) is a relatively accurate predictor of outcome in critically ill patients treated in medical/surgical ICU.
M Jabalameli, Shahshahan, AR Azizian
doaj  

Risk Factors Associated with Development of Acute and Sub-Acute Post-Cesarean Pain: A Prospective Cohort Study

open access: yesJournal of Pain Research, 2020
Jason Ju In Chan,1 Chin Wen Tan,1,2 Cheng Teng Yeam,2 Rehena Sultana,3 Alex Tiong Heng Sia,1,2 Ashraf Samir Habib,4 Ban Leong Sng1,2 1Department of Women’s Anesthesia, KK Women’s and Children’s Hospital, Singapore; 2Anesthesiology and ...
Chan JJI   +6 more
doaj  

Resolving the Uncertainty of Preterm Symptoms: Women’s Experiences With the Onset of Preterm Labor [PDF]

open access: yes, 2002
Objective: To describe expectant women\u27s experiences with the onset of preterm labor. Design: Qualitative, using grounded theory methods. Setting: Southwestern tertiary women\u27s hospital.
Harris, Susan   +2 more
core   +1 more source

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