Results 151 to 160 of about 787,988 (430)
Advanced Science, EarlyView.COL1A1, a major component of ECM, contributes to chemoresistance and poor prognosis in ovarian cancer. Halofuginone (HF) attenuates CAF‐secreted COL1A1 through mTOR‐eIF2α‐ATF4 axis. Notably, HF disrupts collagen deposition to form the looser ECM and facilitates CD8+ T cell infiltration, partially via M2‐M1 macrophage polarization to enhance ...
Wenxin Li +8 more
wiley +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Advanced Science, EarlyView.A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang +14 more
wiley +1 more source
The International Journal of Health Planning and Management, Volume 37, Issue S1, Page 79-100, December 2022., 2022 Abstract Background Low‐ and middle‐income countries worldwide are striving to achieve universal health coverage (UHC), frequently through expansion of statutory health insurance schemes. However, oftentimes evidence is lacking on progress towards quality patient‐centred care and out‐of‐pocket expenditure (OOPE), particularly for poor population groups.
Viktoria Couturier +3 more
wiley +1 more source
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Advanced Science, EarlyView.Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li +11 more
wiley +1 more source
Conceiving Naturally After IVF: the effect of assisted reproduction on obstetric interventions and child health at birth [PDF]
arXivA growing share of the world's population is being born via assisted reproductive technology (ART), including in-vitro fertilisation (IVF). However, two concerns persist. First, ART pregnancies correlate with predictors of poor outcomes at birth--and it is unclear whether this relationship is causal. Second, the emotional and financial costs associated
arxiv
Indications and contraindications for the use of pituitary extract in obstetrics [PDF]
, 1922 Roland S. Cron
openalex +1 more source
What explains variation in the costs of treating patients in English obstetrics specialties? [PDF]
We assess patients admitted to English obstetrics departments to identify what proportion of variation in their costs is explained by patient characteristics and what proportion is due to departmental characteristics.
Andrew Street +2 more
core
Gestational Diabetes Mellitus (GDM) : excellent control or non-disease [PDF]
, 1993 The National Diabetes Data Group makes the case for universal screening of the obstetrical population. The American College of Obstetrics and Gynaecology (ACOG), falls short of recommending universal screening, and suggests instead that screening should ...
Xuereb, Dennis
core
Gestational dating by metabolic profile at birth: a California cohort study. [PDF]
, 2016 BackgroundAccurate gestational dating is a critical component of obstetric and newborn care. In the absence of early ultrasound, many clinicians rely on less accurate measures, such as last menstrual period or symphysis-fundal height during pregnancy, or
Baer, Rebecca J +4 more
core +1 more source