Results 31 to 40 of about 91,849 (262)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Perceptions of House Officers Working in Obstetrics and Gynaecology Department Regarding their Training

Journal of Shalamar Medical & Dental College, 2019
Background: House job is a challenging stage in doctor’s career in which they learn how to apply knowledge which they have obtained from their medical school in practice.
Shaherzad Sohail, Lubna Riaz Dar, Fouzia Umber Qureshi   +2 more
doaj   +1 more source

Evaluation of blood transfusion practice in obstetrics and gynaecology at a tertiary hospital in Port Harcourt, Nigeria

Nigerian Journal of Medicine, 2023
Background: Blood transfusion is an important part of patient management in obstetrics and gynaecology. There is a need to periodically assess blood transfusion practices in order to identify areas for improvement.
Simeon Chijioke Amadi, Peter Abiye Awoyesuku, Hannah E Omunakwe, Linda Anucha Dublin-Green, Uduak Solomon Ocheche, Chinweowa Ohaka   +5 more
doaj   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

Advanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck   +4 more
wiley   +1 more source

Professor of the Imperial Medical-Surgical Academy V.M. Florinsky – Scientist, Teacher and Statesman

Развитие образования, 2019
The main periods of life, scientific and state activity of Vasilij Markovich Florinsky. The purpose of the article is to consider stages of V.M.
Alexander A. Dvirskii, Anatoly E. Dvirsky, Igor I. Ivanov   +2 more
doaj   +1 more source

Recommendations for Thrombopropylaxis in Obstetrics and GynaecologyA SASOG Guideline

South African Journal of Obstetrics and Gynaecology, 2018
BackgroundVenous thrombo-embolism (VTE) is associated with considerable morbidity, mortality in the absence of thromboprophylaxis.MethodThe Southern African Society of Thrombosis and Haemostasis reviewed the available literature and comprehensive ...
Elise Schapkaitz
doaj   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Introduction of an undergraduate interprofessional simulation based skills training program in obstetrics and gynaecology in India

Advances in Simulation, 2019
Interprofessional simulation based education (SBE) improves core clinical skills and team training in obstetrics and gynaecology. In this innovative study, the introduction of an undergraduate interprofessional SBE program for teaching obstetrics and ...
Suhas Gorantla, Utkarsh Bansal, Jai Vir Singh, Akhilesh Dutta Dwivedi, Atul Malhotra, Arunaz Kumar   +5 more
doaj   +1 more source