Results 101 to 110 of about 545,995 (304)

Radical vulvectomy with a bilateral pudendal flap in the treatment of a vulvar cancer relapse

Clinical Case Reports, 2017
Key Clinical Message One of the main risk factors for relapse in vulvar cancer after lymph‐node metastases is free surgical margins. In the case of a relapse, radical vulvectomy with perineal reconstruction is the first choice. Perineal reconstruction is
Begoña Díaz de laNoval
doaj   +1 more source

Gynecology and Obstetrics

Clinical and Applied Thrombosis/Hemostasis, 2013
A. Nicolaides, J. Fareed, A. K. Kakkar, A. J. Comerota, S. Z. Goldhaber, R. Hull, K. Myers, M. Samama, J. Fletcher, E. Kalodiki, D. Bergqvist, J. Bonnar, J. A. Caprini, C. Carter, J. Conard, B. Eklof, I. Elalamy, G. Gerotziafas, G. Geroulakos, A. Giannoukas, I. Greer, M. Griffin, S. Kakkos, M. R. Lassen, G. D. O. Lowe, A. Markel, P. Prandoni, G. Raskob, A. C. Spyropoulos, A. G. Turpie, J. M. Walenga, D. Warwick   +31 more
openaire   +3 more sources

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

“Intrapericardial Approach” for Venous Outflow Reconstruction in Living‐Donor Liver Transplantation for Budd‐Chiari Syndrome: Surgical Techniques and LongTerm Outcomes

Annals of Gastroenterological Surgery, EarlyView.
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata, Tetsuya Tajima, Satoshi Ogiso, Shinji Uemoto, Etsuro Hatano   +4 more
wiley   +1 more source

Basal Body Temperature Assessment: Is It Useful to Couples Seeking Pregnancy? [PDF]

, 2005
Advanced practice nurses in primary care settings are often asked to give appropriate advice to couples seeking pregnancy. This article examines the issue of basal body temperature (BBT), a time-honored way to establish the presence of ovulatory cycles ...
Barron, Mary Lee, Fehring, Richard
core   +1 more source

MTCA‐Net: Multi‐Task Cascade Analysis Network for Real‐Time Sperm Quality Analysis

Advanced Intelligent Systems, EarlyView.
This article proposes MTCA‐Net, a multi‐task cascaded analysis network for real‐time sperm quality assessment in intracytoplasmic sperm injection. The framework integrates detection, tracking, and segmentation modules to jointly analyze sperm morphology and motility.
Jiajin Li, Wenwen Sun, Jun He, Xinyu Fan, Xuecheng Ge, Fengya Lu, Yadan Wang, Yi Wang, Zhiguo Zhang, Qibing Wu, Jinhua Zhou   +10 more
wiley   +1 more source

The Novel ACTC1 p.Gly50Ser Variant Is Associated With Arrhythmia and Secondary Features of HCM Without Hypertrophy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The key diagnostic criterion for hypertrophic cardiomyopathy is the presence of otherwise unexplained hypertrophy. Current definitions of HCM rely on specific thresholds to establish a diagnosis, while guideline directed risk stratification algorithms take its magnitude into consideration.
Thomas D. Gossios, Dimitrios Ntelios, Thomas Zegkos, Despoina Parcharidou, Pavlos Rouskas, Sotirios Katranas, Ioannis Papoulidis, Vlasis Ninios, Antonios Ziakas, Georgios K. Efthimiadis   +9 more
wiley   +1 more source

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman, Carli M. Tops, Jelmer Legebeke, Ting Yang, Marcos Díaz Gay, Diantha Terlouw, Lisa E. E. L. O. Lashley, Stefan Aretz, Anna K. Sommer, Mariona Terradas, Laura Valle, Richarda M. de Voer, Ludmil B. Alexandrov, Hans Morreau, Tom van Wezel, Maartje Nielsen   +15 more
wiley   +1 more source

Editorial: Editors' showcase: obstetrics and gynecology

Frontiers in Medicine, 2023
Simcha Yagel, Sarah M. Cohen
doaj   +1 more source