Results 161 to 170 of about 539,663 (302)

Comparative Analysis of Septin Modifiers, Forchlorfenuron and UR214‐9, on Mitochondrial Fragmentation and Lytic Cell Death

open access: yesCytoskeleton, EarlyView.
ABSTRACT Septins are conserved GTP‐binding proteins that play key roles in cell division, mitochondrial dynamics and immune responses. Despite their importance to human health, pharmacological compounds to modify septins remain limited. Forchlorfenuron (FCF) was the first small molecule identified to modify septins, disrupting their organisation and ...
Dominik Brokatzky   +4 more
wiley   +1 more source

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia   +11 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

A Robust Multistep Digestion Method for Microplastics Detection in Human Tissue by MicroRaman Analysis

open access: yesDrug Testing and Analysis, EarlyView.
A unified digestion protocol for human biological samples has been developed for microplastics analysis by microRaman Spectroscopy. ABSTRACT The presence of microplastics (MPs) in human tissues has raised growing concerns, necessitating robust protocols for their reliable extraction and analysis.
Jennifer P. Pascali   +7 more
wiley   +1 more source

Preliminary Evidence of the Association Between Binge Eating and Preeclampsia in Pregnant U.S. Military Active‐Duty Service Women

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objectives Binge eating is the most common disordered eating behavior among pregnant women. This study examined the association of binge‐eating frequency with the presence of a self‐reported current preeclampsia diagnosis in a sample of U.S. military active‐duty Service women. Methods Active‐duty Service women (N = 134), 20–27 weeks gestation,
Ruby Schrag   +10 more
wiley   +1 more source

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei   +10 more
wiley   +1 more source

Medical education in Obstetrics and Gynecology: preferences of medical students regarding digital teaching. [PDF]

open access: yesFront Med (Lausanne)
Cirkel C   +5 more
europepmc   +1 more source

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