The human colon: Evidence for degenerative changes during aging and the physiological consequences
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley +1 more source
Predictive factors for functional failure of ventral mesh rectopexy in the treatment of rectal prolapse and obstructed defecation. [PDF]
Solari S+8 more
europepmc +1 more source
Chemotherapy‐Induced Neuropathy Affecting the Gastrointestinal Tract
Chemotherapy (with/without immunotherapy/radiotherapy) may induce neurotoxic effects on the gastrointestinal innervation. Chemotherapy‐induced enteric neuropathy (CIEN) and, probably, neurotoxicity affecting the extrinsic innervation of the gut and the brain underlie the frequent and impactful gut dysfunctions and brain–gut axis (BGA) disorders ...
Gema Vera, Kulmira Nurgali, Raquel Abalo
wiley +1 more source
MR defecography in obstructed Defecation syndrome [PDF]
Saher Mohamed Elfiky+2 more
openalex +1 more source
ABSTRACT Objective To compare head posture and upper spine morphology in hypermobile Ehlers‐Danlos syndrome (hEDS) patients with healthy controls with neutral occlusion. Materials and Methods The study consisted of 27 hEDS patients (23 females, 4 males, mean age 36.41 ± 11.35) and 39 healthy controls (28 females, 11 males, mean age 31.85 ± 11.35) with ...
Ashkan Jasemi+2 more
wiley +1 more source
The elementary obstruction and the Weil restriction [PDF]
In this text we investigate the good behaviour of the elementary obstruction, introduced by Colliot-Thelene and Sansuc. This is an obstruction to the existence of a rational points on certain algebraic varieties. Assuming some conditions on the Picard group, we prove that the elementary obstruction behaves well under the Weil restriction of a variety.
arxiv
Insiders and Outsiders: The Role of Human Agents and Networks in System Change
ABSTRACT This article focuses on the roles of insiders or outsiders in order to theorize the role that human agents play in systems change. It asks: (1) what strengths and weaknesses do insiders and outsiders have respectively as agents of change; and (2) what strategies are available to use these insights to increase, or to limit, the prospects of ...
Miranda Forsyth, Anthea Roberts
wiley +1 more source
Perirectal hematoma after stapled surgery for hemorrhoidal prolapse and obstructed defecation syndrome: case series management to avoid panic-guided treatment. [PDF]
Mascagni D+8 more
europepmc +1 more source
Euler obstruction and Lipschitz-Killing curvatures [PDF]
Applying a local Gauss-Bonnet formula for closed subanalytic sets to the complex analytic case, we obtain characterizations of the Euler obstruction of a complex analytic germ in terms of the Lipschitz-Killing curvatures and the Chern forms of its regular part. We also prove analogous results for the global Euler obstruction.
arxiv
Rodrigo Guzmán Rojas+3 more
openalex +1 more source