Results 1 to 10 of about 499,895 (395)
Frontiers in Cardiovascular Medicine, 2021 Objective: Atrial fibrillation is the most prevalent persistent arrhythmia in patients with hypertrophic obstructive cardiomyopathy. Comparative analyses of the safety and effectiveness of septal myectomy with and without surgical ablation are limited ...
Yanhai Meng +8 more
doaj +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Collagen cross‐linking is covalent bonds among collagen fibers from catalysis of lysyl oxidase (LOX) and advanced glycation end products (AGEs).
Xuanye Bi +6 more
doaj +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background In patients with obstructive hypertrophic cardiomyopathy, surgical myectomy (SM) is indicated for severe symptoms. We sought to compare long‐term outcomes of patients with obstructive hypertrophic cardiomyopathy where SM was based on guideline‐
Alaa Alashi +7 more
doaj +2 more sources
Right Ventricle Outflow Obstruction in Biventricular Hypertrophic Cardiomyopathy in Amyloidosis [PDF]
European Journal of Case Reports in Internal Medicine, 2017 Light-chain (AL) amyloidosis is the most common type of amyloidosis; cardiac involvement is rare but has a poor prognosis. Biventricular hypertrophic cardiomyopathy is an exceptional finding in amyloidosis and its association with obstructive right ...
Hamza Sanoussi +3 more
doaj +5 more sources
European Journal of Heart Failure, 2023 In the EXPLORER‐HCM trial, mavacamten reduced left ventricular outflow tract obstruction (LVOTO) and improved functional capacity of symptomatic hypertrophic obstructive cardiomyopathy (HOCM) patients.
E. Bertero +62 more
semanticscholar +1 more source
Journal of Clinical Medicine, 2023 Alcohol septal ablation is a minimally invasive procedure for the treatment of left ventricular outflow tract (LVOT) obstruction in patients with hypertrophic obstructive cardiomyopathy (HOCM) who remain symptomatic despite optimal medical therapy.
F. Gragnano +15 more
semanticscholar +1 more source
JAMA cardiology, 2022 Importance Patients with hypertrophic obstructive cardiomyopathy (HOCM) and drug-refractory symptoms and outflow gradients have limited nonsurgical treatment options. The feasibility of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA)
M. Zhou +20 more
semanticscholar +1 more source
Effect of Mavacamten on Chinese Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy
JAMA cardiology, 2023 Key Points Question What is the effect of treatment with mavacamten on Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy? Findings In this phase 3 randomized clinical trial of 81 patients, mavacamten significantly improved ...
Z. Tian +15 more
semanticscholar +1 more source
Mavacamten: a first-in-class myosin inhibitor for obstructive hypertrophic cardiomyopathy
European Heart Journal, 2023 Graphical Abstract Graphical Abstract The path to treatment of obstructive hypertrophic cardiomyopathy. (Top left) Haemodynamic observations demonstrated. Left ventricular (LV) obstruction and symptoms related to LV hypertrophy.
E. Braunwald +4 more
semanticscholar +1 more source
Anatolian Journal of Cardiology, 2022 Background: Alcohol septal ablation is recommended for hypertrophic obstructive cardiomyopathy patients who had refractory symptoms despite optimal medical treatment.
Umut Karabulut +5 more
doaj +1 more source