Results 171 to 180 of about 499,895 (395)

Left ventricular flow from apex to base during systole and isovolumic relaxation in a patient with hypertrophic cardiomyopathy and midventricular obstruction [PDF]

, 2017
The occurrence of a left ventricular anterograde flow velocity (maximal: 3·9m . s−1) is demonstrated in a 32-year-old patient with hypertrophic cardioinyopathy and midveniricular obstruction, beginning at early systole and persisting throughout the ...
JENNI, R., KRAYENBÜHL, H. P., SÜTSCH, G.   +2 more
core  

11-beta-KETOTHIOLASE DEFICIENCY WITH OBSTRUCTIVE CARDIOMYOPATHY AND SPECIFIC MORPHOLOGICAL BRAIN DESTRUCTION [PDF]

, 1994
V. Hesse, Hansjosef Böhles, A Sewell, Heike Forster, W Jänisch, Druce Middleton, Holgar Haberland   +6 more
openalex   +1 more source

Left atrial to coronary sinus shunting in more advanced heart failure with preserved ejection fraction

ESC Heart Failure, EarlyView.
Abstract Aims Inter‐atrial shunt device therapy has shown mixed results in clinical trials, with clinical ‘non‐responders’ typically showing features of more advanced heart failure. We aimed to analyse the haemodynamic and clinical response of a novel left atrial to coronary sinus (LA‐CS) shunt device in patients with higher natriuretic peptide (NP ...
Ryan J. Tedford, Brian A. Houston, JoAnn Lindenfeld, Rami Kahwash, Marcus A. Urey, Nicholas S. Amoroso, Benjamin Hibbert, Firas Zahr, William A. Gray, Javed Butler   +9 more
wiley   +1 more source

Case Report: Diagnostic challenges in Fabry disease: misinterpreted obstructive hypertrophic cardiomyopathy and the role of enzyme replacement therapy

Frontiers in Cardiovascular Medicine
Fabry disease (FD) is a rare X-linked inherited lysosomal storage disorder. The abnormal accumulation of metabolic substrates induces inflammation and fibrosis in cells, resulting in organ dysfunction.
Weili Cheng, Mingqiang Ao, Dinghu Xu, Yuqing Zhang, Qin Tao   +4 more
doaj   +1 more source

Inflammatory Serine Proteases Play a Critical Role in the Early Pathogenesis of Diabetic Cardiomyopathy. [PDF]

, 2019
BACKGROUND/AIMS: Diabetic cardiomyopathy (DCM) is characterized by structural and functional alterations that can lead to heart failure. Several mechanisms are known to be involved in the pathogenesis of DCM, however, the molecular mechanism that links ...
Barbery, Carlos, Chaki, Shaswati, Guo, Xinji, Kolpakov, Mikhail A, Qi, Zhao, Rafiq, Khadija, Sabri, Abdelkarim, Sarkar, Amrita, Shukla, Sanket K, Sikder, Kunal   +9 more
core   +1 more source

Prescription of guideline‐directed medical therapy in heart failure: impact on mortality and readmission

ESC Heart Failure, EarlyView.
Routine data analysis showing a better outcome regarding mortality and readmission in HF patients when being prescribed the current four‐drug treatment (vs. the outdated two‐drug therapy) 91–365 days after index hospital stay. Abstract Aims The 2021 European heart failure (HF) guidelines recommend the combination of four drugs as a standard therapy ...
Martin Möckel, Samipa Pudasaini, Kristina Feldmann, Henning Thomas Baberg, Benny Levenson, Jürgen Malzahn, Thomas Mansky, Guido Michels, Christian Günster, Elke Jeschke   +9 more
wiley   +1 more source

Changes in Left Ventricular Diastolic Function 6 Months After Nonsurgical Septal Reduction Therapy for Hypertrophic Obstructive Cardiomyopathy [PDF]

, 1999
Sherif F. Nagueh, Nasser Lakkis, Katherine J. Middleton, Donna Killip, William A. Zoghbi, Miguel A. Quin̄ones, William H. Spencer   +6 more
openalex   +1 more source

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

ESC Heart Failure, EarlyView.
Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem, Teresa C. Leone, Christopher Petucci, Clarissa Shoffler, Ravindra C. Kodihalli, Tiffany Hidalgo, Cheryl Tow‐Keogh, Jessica Mancuso, Iphigenia Tzameli, Donald Bennett, John D. Groarke, Rachel J. Roth Flach, Daniel J. Rader, Daniel P. Kelly   +13 more
wiley   +1 more source

Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy

JACC: Basic to Translational Science, 2019
Summary: Disopyramide is effective and safe in patients with obstructive hypertrophic cardiomyopathy. However, its cellular and molecular mechanisms of action are unknown.
Raffaele Coppini, MD, PhD, Cecilia Ferrantini, MD, PhD, Josè Manuel Pioner, PhD, Lorenzo Santini, MS, Zhinuo J. Wang, PhD, Chiara Palandri, MS, Marina Scardigli, PhD, Giulia Vitale, MS, Leonardo Sacconi, PhD, Pierluigi Stefàno, MD, Laura Flink, MD, Katherine Riedy, MD, Francesco Saverio Pavone, PhD, Elisabetta Cerbai, PhD, Corrado Poggesi, MD, Alessandro Mugelli, MD, Alfonso Bueno-Orovio, PhD, Iacopo Olivotto, MD, Mark V. Sherrid, MD   +18 more
doaj  

New concepts of intramural myocardial conduction in hypertrophic obstructive cardiomyopathy.

, 1968
J J Coyne
openalex   +1 more source