Results 281 to 290 of about 67,015 (304)
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Korean Circulation Journal
Author's summary Mavacamten, a selective allosteric cardiac myosin inhibitor, brought a transformative shift in the therapeutic landscape of obstructive hypertrophic cardiomyopathy (oHCM). Yet, its real-world evidence in Asians is limited.
Jaehyun Lim +15 more
semanticscholar +1 more source
Author's summary Mavacamten, a selective allosteric cardiac myosin inhibitor, brought a transformative shift in the therapeutic landscape of obstructive hypertrophic cardiomyopathy (oHCM). Yet, its real-world evidence in Asians is limited.
Jaehyun Lim +15 more
semanticscholar +1 more source
Aficamten for Obstructive Hypertrophic Cardiomyopathy
New England Journal of MedicineJorge, Pedreira-Bouzas +2 more
openaire +4 more sources
Hypertrophic obstructive cardiomyopathy
American Heart Journal, 1972L A, Jacobs, R D, Yee, P N, Yu
+8 more sources
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease
Background Aficamten, a novel cardiac myosin inhibitor, reversibly reduces cardiac hypercontractility in obstructive hypertrophic cardiomyopathy. We present a prespecified analysis of the pharmacokinetics, pharmacodynamics, and safety of aficamten in ...
C. Coats +35 more
semanticscholar +1 more source
Background Aficamten, a novel cardiac myosin inhibitor, reversibly reduces cardiac hypercontractility in obstructive hypertrophic cardiomyopathy. We present a prespecified analysis of the pharmacokinetics, pharmacodynamics, and safety of aficamten in ...
C. Coats +35 more
semanticscholar +1 more source
Hypertrophic Obstructive Cardiomyopathy.
Archives of Internal Medicine, 1970Dr. Meerschwam has prepared a monograph on a very interesting condition known, in the United States, mostly, as idiopathic hypertrophic subaortic stenosis. He has painstakingly followed a series of his own patients, reviewed the world literature on the subject, and prepared a most thorough bibliography.
+4 more sources
[Hypertrophic obstructive cardiomyopathy].
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1990Today, with the help of modern echocardiographic techniques we are able not only to describe the characteristic changes when a HOCM is present and to determine the intracavitary pressure gradient, but also recognize the functional irregularities typical for the HOCM.
H, Goos, B, Krosse, P, Ewers
openaire +1 more source
The American Journal of Cardiology, 1998
A rare case of obstructive hypertrophic cardiomyopathy (HC) with mitral regurgitation (MR) is reported, which developed over 7 years from nonobstructive HC in an elderly woman. Systolic anterior motion of the anterior mitral leaflet was the most likely cause of the outflow obstruction and mitral valve replacement combined with septal myectomy resulted ...
M, Horimoto +6 more
openaire +2 more sources
A rare case of obstructive hypertrophic cardiomyopathy (HC) with mitral regurgitation (MR) is reported, which developed over 7 years from nonobstructive HC in an elderly woman. Systolic anterior motion of the anterior mitral leaflet was the most likely cause of the outflow obstruction and mitral valve replacement combined with septal myectomy resulted ...
M, Horimoto +6 more
openaire +2 more sources
Dynamic obstruction in hypertrophic cardiomyopathy
Current Opinion in Cardiology, 2015The present article reviews the recent advances in the echocardiographic assessment of left ventricular outflow tract (LVOT) obstruction in hypertrophic cardiomyopathy (HCM). In particular, it highlights the role of novel imaging techniques in promoting our understanding of the pathophysiology of obstruction and discusses the prognostic value of ...
Bogdan A, Popescu +2 more
openaire +2 more sources
Hypertrophic Obstructive Cardiomyopathy
2015Hypertrophic Cardiomyopathy (HCM) is a disorder which causes hypertrophy of the interventricular septum of the heart, leading to obstruction of left ventricular outflow during systole. The murmur that is pathognomonic for HCM is a crescendo-decrescendo holosystolic murmur best heard at the left sternal boarder.
openaire +1 more source