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Obstructive Sleep Apnea

Comprehensive Physiology, 2012
Abstract Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive collapse of the pharyngeal airway during sleep. Control of pharyngeal patency is a complex process relating primarily to basic anatomy and the activity of many pharyngeal dilator muscles.
David P, White, Magdy K, Younes
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Obstructive Sleep Apnea

Clinics in Chest Medicine, 1985
This chapter provides an account of obstructive sleep apnea that is designed for clinicians. Current ideas about the mechanism of upper airway obstruction are reviewed, and the clinical features are discussed in a manner intended to facilitate the clinical assessment of such patients.
C E, Sullivan, F G, Issa
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Sleep Deficiency in Obstructive Sleep Apnea

Clinics in Chest Medicine, 2022
Sleep deficiency in patients with obstructive sleep apnea includes abnormal quality, timing, and duration of sleep, and the presence of other comorbid conditions. These include insomnia, circadian misalignment disorders, and periodic limb movements of sleep.
Olurotimi, Adekolu, Andrey, Zinchuk
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Obstructive sleep apnea

Current Treatment Options in Neurology, 2004
Obstructive sleep apnea (OSA) is a major public health problem in the US that afflicts at least 2% to 4% of middle-aged Americans and incurs an estimated annual cost of 3.4 billion dollars. At Stanford, we utilize a multispecialty team approach combining the expertise of sleep medicine specialists (adult and pediatric), maxillofacial and ear, nose, and
Christian, Guilleminault   +1 more
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Obstructive Sleep Apnea

New England Journal of Medicine, 1996
Our understanding of the nature and consequences of upper-airway obstruction in adults during sleep has evolved considerably over the past two decades. Sleep apnea — defined as repeated episodes of obstructive apnea and hypopnea during sleep, together with daytime sleepiness or altered cardiopulmonary function — is common.1 Epidemiologic studies ...
P J, Strollo, R M, Rogers
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Opioids and obstructive sleep apnea

Journal of Clinical Sleep Medicine, 2022
Opioids are widely prescribed for pain management, and it is estimated that 40% of adults in the United States use prescription opioids every year. Opioid misuse leads to high mortality, with respiratory depression as the main cause of death. Animal and human studies indicate that opioid use may lead to sleep-disordered breathing.
Carla, Freire   +2 more
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Obstructive Sleep Apnea

Pediatric Clinics of North America, 1989
Obstructive sleep disorders and apnea are commonly seen in children of all ages. The obstruction usually causes snoring and varying periods of interrupted breathing during sleep. Obstructive sleep disorders cause multiple physiologic disturbances and should be treated before they become severe.
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Obstructive Sleep Apnea

Annals of Internal Medicine, 2005
Obstructive sleep apnea remains an important public health problem because of its neurocognitive sequelae.
Sean M, Caples   +2 more
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Obstructive Sleep Apnea

JAMA, 2000
Obstructive sleep apnea (OSA) is a prevalent disorder, affecting 2% to 4% of the adult population [1]. It is characterized by recurrent apneas and hypopneas during sleep with resultant oxyhemoglobin desaturations and sleep fragmentation. The clinical sequelae of OSAmay be severe and include daytime hypersomnolence, cognitive impairment, systemic and/or
J F, Piccirillo   +2 more
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Obstructive Sleep Apnea

Annals of Internal Medicine, 2019
Obstructive sleep apnea (OSA) is very common but is frequently undiagnosed. Symptoms include loud snoring, nocturnal awakening, and daytime sleepiness. Motor vehicle accidents due to drowsy driving are a particular concern. Evaluation and treatment should focus on symptomatic patients, both to alleviate symptoms and to potentially decrease ...
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