Results 51 to 60 of about 75,538 (267)
Development of a nalmefene formulation suitable for a community‐use auto‐injector
British Journal of Clinical Pharmacology, EarlyView.Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Sleep Fragmentation in Obstructive Sleep Apnea [PDF]
Sleep, 1996 Obstructive sleep apnea is associated with fragmentation of sleep due to the repeated occurrence of end-apneic arousal throughout the night. Arousals are provoked by stimuli generated during upper airway obstruction. Mechanoreceptor stimuli produced during obstructed inspiratory efforts appear to play a major role in mediating the end-apneic arousal ...
openaire +2 more sources
مجله دانشکده پزشکی اصفهان, 2016 Background: Obstructive sleep apnea and stroke are the most common diseases worldwide and especially in our country. Previous studies showed that both above diseases are common risk factors and in some of study co-morbidity to stroke and obstructive ...
Mohammadreza Najafi, Sara Hoseinpour
doaj
British Journal of Clinical Pharmacology, EarlyView.Aims The glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) semaglutide and liraglutide are approved for chronic weight management. Both drugs also have favourable effects on the risk of developing diabetes and cardiovascular disease (CVD) compared with placebo, but their comparative effectiveness for these outcomes is unclear.
Ethan J. Cannon +7 more
wiley +1 more source
Obstructive Sleep Apnea and Aldosterone [PDF]
Sleep, 2009 Obstructive sleep apnea (OSA) is a major risk factor for hypertension and has been associated with increased risk for cardiovascular morbidity. A dysregulated renin-angiotensin-aldosterone system may contribute to excess sodium retention and hypertension and may be activated in OSA.
Anna, Svatikova +6 more
openaire +2 more sources
What Is the Pterygomandibular Raphe? A Confluence of Fasciae Rather Than a Discrete Structure
Clinical Anatomy, EarlyView.ABSTRACT The pterygomandibular raphe (PMR) has traditionally been described as a fibrous or tendinous band connecting the bucinator (BM) and superior pharyngeal constrictor (SPCM) muscles. However, recent evidence has questioned its existence. This study aimed to reevaluate the anatomy of the pterygomandibular region by preserving fascial continuity ...
Joe Iwanaga +10 more
wiley +1 more source
Cardioversion of atrial fibrillation does not affect obstructive sleep apnea
Upsala Journal of Medical Sciences, 2017 Background: Sleep apnea is common in patients with atrial fibrillation, but the effect of the cardioversion of atrial fibrillation to sinus rhythm on central and obstructive apneas is mainly unknown.
Niklas Höglund +4 more
doaj +1 more source
Implant‐related orofacial pain managed with implant apicoectomy: A case report
Clinical Advances in Periodontics, EarlyView.Abstract Background In recent years, the use of implants has emerged as a widely accepted method for the replacement of missing teeth. Although rare, chronic pain associated with implant placement has been reported in the literature. Conversely, apicoectomy, the removal of the apical portion has been integrated into the implantology field in cases with
Oscar Durán‐Garnica +4 more
wiley +1 more source
Евразийский Кардиологический Журнал, 2016 The aim. The study and analysis of cardiac arrhythmias, heart rhythm variability in patients with ischemic heart disease, obstructive sleep apnea and primary snoring. Material and methods.
E. S. Tarasik +2 more
doaj +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Pharmacological mechanisms and physiologic effects of GLP‐1 receptor agonists relevant to peri‐endoscopic risk. ABSTRACT The global increase in obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD) has led to a higher use of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) among patients ...
Junaid Beig +7 more
wiley +1 more source