Results 51 to 60 of about 16,523 (242)

Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression

Annals of Neurology, EarlyView.
Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low, Jeffrey L. Gunter, Mingzhao Hu, Sheelakumari Raghavan, Scott A. Przybelski, Christopher G. Schwarz, Kejal Kantarci, Val J. Lowe, Ronald C. Petersen, Jonathan Graff‐Radford, Clifford R. Jack Jr, Prashanthi Vemuri   +11 more
wiley   +1 more source

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

Annals of Neurology, EarlyView.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti, Nicolas R. Barthélemy, Kanta Horie, Cindy V. Ly, Kaleigh F. Roberts, Srinivas Koutarapu, Richard J. Perrin, Erin E. Franklin, Chiara Pedicone, Joshua Orrick, Justin Melendez, Timothy M. Miller, Chihiro Sato, Nupur Ghoshal, Alison M. Goate, Celeste M. Karch, Randall J. Bateman, Soumya Mukherjee   +17 more
wiley   +1 more source

Toward Comprehensive Climate Action: Assessing Mitigation Approaches Across Canadian Municipalities

Environmental Policy and Governance, EarlyView.
ABSTRACT Local governments are widely regarded as key leaders in the global response to climate change. Understanding if and how municipalities commit to climate mitigation is crucial for assessing their contribution to global emission‐reduction goals and identifying barriers to effective climate transitions.
Aryana Soliz, Adriane MacDonald, David Talbot, Eduardo Ordonez‐Ponce, Ying Zhou, Samantha Hall Linton, Amelia Clarke, Amr ElAlfy   +7 more
wiley   +1 more source

Enhancing Optical Camera Communication Performance for Collaborative Communication Using Positioning Information

IEEE Access
Optical camera communication (OCC) has emerged as a promising alternative technology for radio frequency (RF)-based communication systems. However, existing OCC approaches only consider transmitting data through broadcasting, without any ability for ...
Ida Bagus Krishna Yoga Utama, Ones Sanjerico Sitanggang, Muhammad Rangga Aziz Nasution, Md. Ibne Joha, Jaejun Yoo, Yeong Min Jang   +5 more
doaj   +1 more source

Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells

Biology Open, 2014
Occludin is the first identified protein in the tight junction (TJ), but its function has remained for the most part obscure. TJs have been demonstrated to play important roles in the inner ear function, and occludin is expressed in all the epithelial ...
Shin-ichiro Kitajiri, Tatsuya Katsuno, Hiroyuki Sasaki, Juichi Ito, Mikio Furuse, Shoichiro Tsukita   +5 more
doaj   +1 more source

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil, Margaret M. Donahue, Cathy B. Dang, Gergely Tarcsay, Laura A. Ewell   +4 more
wiley   +1 more source

Whipped yogurt with organic panela and coffee: an innovation for the dairy industry [PDF]

Brazilian Journal of Food Technology
Whipped yogurts were developed using organic ingredients, including organic granulated panela (OGP) and organic coffee concentrate (OCC). This study aimed to evaluate the effects of varying levels of OGP (12% and 18%) and OCC (2%, 3%, and 4%) on the ...
Demetrio Javier Aponte Elera, Nilda Doris Montes Villanueva, William Nemesio Chunga Trelles   +2 more
doaj   +1 more source

A Numerical Investigation of the Effects of Piston Bowl Geometry and Spray Angle on Combustion, Performance and Emission of a Diesel Engine

Energy Science &Engineering, EarlyView.
A piston bowl's design and spray angle improve air‐fuel mixing, resulting in more complete combustion and higher efficiency. Ansys Forte 2023 R1 a CFD software was used to analyze the effects of five combustion chamber geometries of cylinder, modified re‐entrant, re‐entrant, double‐stepped, and stepped on engine performance, combustion, and emission ...
Md. Nazmul Haque, Abdullah Al Rifat, Tafsirul Hassan, Md. Ifthaker Alam, Mohammad Mehedi Hasan Kazol, Md. Ashraful Islam, Abidur Rahman Adib, Mizanur Rahman   +7 more
wiley   +1 more source

IMRT in oral cavity cancer

Radiation Oncology, 2007
Background Except for early T1,2 N0 stages, the prognosis for patients with oral cavity cancer (OCC) is reported to be worse than for carcinoma in other sites of the head and neck (HNC). The aim of this work was to assess disease outcome in OCC following
Davis Bernard J, Graetz Klaus W, Zwahlen Roger A, Studer Gabriela, Glanzmann Christoph   +4 more
doaj   +1 more source

Poor Diet and Oral Cavity Cancer Risk in Smoking and Non‐Smoking Men and Women: An Analysis of Three US Cohorts

Head &Neck, EarlyView.
ABSTRACT Introduction Oral cavity cancer (OCC) incidence is rising among non‐smokers and younger individuals without traditional risk factors. While carcinogenic exposures such as tobacco and alcohol are well studied, the association between unhealthy dietary patterns and OCC has been minimally explored.
Mateo Useche, Luis Gomez‐Castillo, Kara Cushing‐Haugen, Rocco Ferrandino, Neal Futran, Emily Marchiano, Cristina P. Rodriguez, Holly R. Harris, Brittany Barber   +8 more
wiley   +1 more source