Results 141 to 150 of about 1,142 (243)

Comparison of clinical research trends and hotspots in allergic rhinitis and asthma from 2013 to 2023 based on bibliometric analysis. [PDF]

Heliyon
Zhao L, Yang J, Liu T, Cao H, Liang Y, Wang B.   +5 more
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

miRNA Expression Profile in Whole Blood of Healthy Volunteers and Moderate Beer Consumption with Meals. [PDF]

Nutrients
Padro T, Escate R, Badimon L.
europepmc   +1 more source

Associations between Polyfluoroalkyl Substances Exposure and Breast Cancer: A Meta-Analysis. [PDF]

Toxics, 2022
Jiang H, Liu H, Liu G, Yu J, Liu N, Jin Y, Bi Y, Wang H.   +7 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Spatial Study of TLR4, TLR5 and TLR9 in Gastric Premalignant Lesions Before and After <i>Helicobacter pylori</i> Eradication. [PDF]

Int J Mol Sci
Villarroel-Espíndola F, Jaupi L, Reyes J, Barrientos C, Podestá C, Selman C, Bizama C, Corvalan A, Gonzalez-Stegmaier R, Jara-Rosales S, Bascur P.   +10 more
europepmc   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Obadia Lionel, Le Bouddhisme en Occident

Recherches Sociologiques et Anthropologiques, 2007
Olivier Servais
doaj   +1 more source

Why and when successful rural malaria control became a local problem - Palestine 1922. [PDF]

Malariaworld J
Alexander A.
europepmc   +1 more source