Results 41 to 50 of about 1,142 (243)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Les nouveaux choix diplomatiques de la RD Congo : l’axe Extrême –Orient et la réaction de l’occident [PDF]

open access: yesMouvements et Enjeux Sociaux
La présente étude se propose de démontrer les nouvelles motivations diplomatiques de la RDC face à certaines puissances émergentes de l’Extrême-Orient.
Sylvain TSHIBANGU MUKENG   +1 more
doaj  

Resenha de: Les temps apostoliques

open access: yesRevista de História, 1971
     DAUVILLIER (Jean) . — Les temes apostoliques (Ier siècle) (2.° tomo). Coleção "Histoire du Droit et des Institutions de 1'Eglise en Occident''. Paris. Éditions Sirey. XVIII 744 pp. Preço: 130 F. 
Eurípedes Simões de Paula
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Arab Representations of the Occident

open access: yesAmerican Journal of Islam and Society, 2008
In his Orientalism (Vintage Books: 1978), literature teacher and cultural critic Edward Said claimed that the entire corpus of academic, literary, and artistic knowledge about the Orient in general and theMuslim world in particular that the West had ...
Naama Ben-Ami
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

The Anti-Oriental Narrative of Vambery in Travels in Central Asia [PDF]

open access: yesInternational Journal of English Language and Translation Studies, 2018
A reader of Travels in Central Asia by Vambery expects a reliable and authentic picture of the history of orient; however, what he/she receives is nothing but a biased and prejudiced narrative mingled with misguided epistemological understanding on the ...
Aijeran Paidar , Behzad Pourqarib
doaj  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

La perception de « Hayy ben Yaqdhan » en Occident latin [PDF]

open access: yesAnnales du Patrimoine, 2011
Dr Chokri Mimouni, La perception de « Hayy ben Yaqdhan » en Occident ...
Dr Chokri Mimouni
doaj  

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