Results 41 to 50 of about 1,228 (259)

« L’Autre » peut-il invertir le cadrage dans le champ des études touristiques ?

Via@, 2020
Cet essai est né du malaise et des questions que suscite le constat du peu d’attention qu’accorde la recherche touristique au touriste non-occidental. J’ai alors tenté de réagir à cette carence en présentant les photographies prises en Occident par des ...
Sarani Pitor Pakan
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Les nouveaux choix diplomatiques de la RD Congo : l’axe Extrême –Orient et la réaction de l’occident [PDF]

Mouvements et Enjeux Sociaux
La présente étude se propose de démontrer les nouvelles motivations diplomatiques de la RDC face à certaines puissances émergentes de l’Extrême-Orient.
Sylvain TSHIBANGU MUKENG, ANTONIO QUILA GARCIA MIALA   +1 more
doaj  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Resenha de: Les temps apostoliques

Revista de História, 1971
     DAUVILLIER (Jean) . — Les temes apostoliques (Ier siècle) (2.° tomo). Coleção "Histoire du Droit et des Institutions de 1'Eglise en Occident''. Paris. Éditions Sirey. XVIII 744 pp. Preço: 130 F. 
Eurípedes Simões de Paula
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

La creación de un nuevo léxico ético y político en la obra jurídica de Alfonso X el Sabio: un breve glosario

E-Spania, 2020
L’oeuvre juridique alphonsine et, en particulier, Las Siete Partidas, jette les bases d’un discours politique ambitieux, qui propose la traduction et l’interprétation de certains concepts clés de la philosophie aristotélicienne.
Irina Nanu
doaj   +1 more source

Historical Reflections on Islam and the Occident [PDF]

European Review, 2012
The media and political scientists create the impression that the world of Islam and the Occident are two totally different civilizations. The author shows, on the contrary, that life in the 14 centuries of the Christian Middle Ages and the Ancien Régime – Old Europe – was in many ways similar to that of the area's Muslim neighbours, and only moved ...
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source