Results 171 to 180 of about 37,221 (250)

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, Volume 36, Issue 4, July 2026.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

The enigmatic occipital emissary vein, foramina, and canals: anatomical study with application to skull base surgery. [PDF]

Neurosurg Rev
Campbell A, Hines B, Baudoin JM, Komune N, Donofrio CA, Badaloni F, Fioravanti A, Iwanaga J, Aslam R, Johnson K, Lockwood J, Dumont AS, Tubbs RS.   +12 more
europepmc   +1 more source

Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain

Advanced Materials, Volume 38, Issue 32, 8 June 2026.
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha, Bilguun Nurzed, Mostafa Berangi, Andre Kuehne, Helmar Waiczies, Igor Fabian Tellez Ceja, Xiang Hu, Thomas Gladytz, Lisa Krenz, Dave Huebler, Beate Endemann, Claudia Brockmann, Ebba Beller, Oliver Stachs, Thoralf Niendorf   +14 more
wiley   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1192-1203, June 2026.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Occipital abscess associated with cholesteatoma: a case illustrating possible infectious spread. [PDF]

Braz J Otorhinolaryngol
Saha KL, Bhowmik B.
europepmc   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Cranial Suture Joints in Sheep <i>Ovis aries</i> (<i>Najdi breed</i>): Anatomical and Radiographic Findings. [PDF]

Vet Sci
Alshanbari FA, Allouch GM, Sadan M, Salouci M.   +3 more
europepmc   +1 more source

Repair of Occipital Bone Defects in Neurofibromatosis Type 1 by Means of CAD/CAM Prefabricated Titanium Plates. [PDF]

Craniomaxillofac Trauma Reconstr, 2018
Friedrich RE, Emami P, Hagel C, Wikner J, Hanken H.   +4 more
europepmc   +1 more source

New Insights Into Cranial Base Ontogeny in Modern Humans Through Morphometric Analysis

American Journal of Biological Anthropology, Volume 190, Issue 2, June 2026.
ABSTRACT Objectives The cranial base is located at the interface between the face, the brain, and the vertebral column. Understanding its growth is essential for elucidating key aspects of craniofacial development, neurodevelopment, and locomotor function.
Amaëlle Sourbé, Mathilde Savignat, Frédéric Santos, Thomas Colard   +3 more
wiley   +1 more source

Automated Measurement of Occipito-Axial Angle on Cervical Radiographs Using a Deep Learning Object Detection Model: A Proof-of-Concept Study. [PDF]

Neurospine
Yamamoto S, Fuse Y, Nagashima Y, Mori K, Abe T, Matsuo M, Gonda T, Hata N, Nishimura Y, Saito R.   +9 more
europepmc   +1 more source