Results 311 to 320 of about 205,837 (394)

The Syk inhibitor BI 1002494 impairs thrombus infill in a murine femoral artery occlusion without affecting hemostasis. [PDF]

Blood Vessel Thromb Hemost
Faruque MO, Pokrovskaya ID, Ball KK, Webb MW, Rhee SW, Storrie B.   +5 more
europepmc   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Comparing Iliac Artery Sizes to Explain Post-EVAR Non-Obstructive Thrombosis. Comment on Lee et al. Influence of Aortoiliac Geometry on Non-Occlusive Thrombotic Risk Following Endovascular Repair of Abdominal Aortic Aneurysms. <i>Diagnostics</i> 2025, <i>15</i>, 2134. [PDF]

Diagnostics (Basel)
Kok W.
europepmc   +1 more source

Multifunctional Programmable Transmissive Metasurface with Phase and Amplitude Manipulation Capability

Advanced Science, EarlyView.
This work provides a multifunctional programmable transmissive metasurface with phase and amplitude manipulation capability in the sub‐6G band. By applying different coding strategies, the proposed metasurface can realize vortex beam generation, holographic imaging under phase coding mode, and multi‐beam forming in phase‐amplitude joint coding mode ...
Hao Tian Shi, Rui Yuan Wu, Shi He, Xue Yun Guo, Xiao Qing Chen, Yi Ning Zheng, Bing Bing Zhu, Lei Zhang, Tie Jun Cui   +8 more
wiley   +1 more source

Clinical data comparison for FDA-approved gene therapies in sickle cell disease. [PDF]

Exp Biol Med (Maywood)
Leonard A, Kanter J.
europepmc   +1 more source

Le cancer colo-rectal à la Réunion : fréquence des formes occlusives et perforées

, 2017
Antoine Robert
openalex   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Herpes Simplex Virus-2-Associated Retinal Vasculitis Without Clinically Evident Necrosis: Expanding the Spectrum of Herpetic Retinitis. [PDF]

Cureus
Markan A, Tripathi M, Makashir M.
europepmc   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

An Unexpected Complication of Training: A Rare Case of Paget-Schroetter Syndrome in an Adolescent Athlete. [PDF]

Cureus
Abouafech A, Oar DP, Chapman SR, Singh G, Westfall S, Bhagratie J.   +5 more
europepmc   +1 more source