Results 41 to 50 of about 1,640,239 (164)

Study on methylation level of replication related genes of occult hepatitis B virus

Zhongguo shuxue zazhi, 2022
Objective To study the level of occult hepatitis B virus methylation and replication related genes, and to explore the effect of the former on the latter.
Meilin ZHANG, Ruitao WANG, Shan WANG, Maimaiti HA Limire, Xinjing FU, Lijun ZHOU   +5 more
doaj   +1 more source

Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]

, 2011
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Nashwa Abousamra, Azza Azza Abdel-Aziz, Mona Elhadidy, Mohamed Abd-elmaksoud, Yahia Gad, Nasser Mousa   +5 more
core  

Site‐specific O‐glycans influence lacritin structure and multimerization in tears

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Lacritin is an abundantly expressed glycoprotein in tear fluid and plays key roles in immune response, tear secretion, and bacterial killing. These biological functions are tightly regulated through several biochemical mechanisms including multimerization, proteolysis, and alternative splicing, especially within its C‐terminal domain.
Vincent Chang, Ryan J. Chen, Isaac Lian, Madilynn Hamilton, Keira E. Mahoney, Jeff Romano, Gordon Laurie, Stacy A. Malaker   +7 more
wiley   +1 more source

Correlation Between the Hepatic Expression of Human MicroRNA hsa-miR-125a-5p and the Progression of Fibrosis in Patients With Overt and Occult HBV Infection

Frontiers in Immunology, 2018
AimsTo evaluate the correlation between the hepatic expression pattern of hsa-miR-125a-5p and HBV-DNA and the progression of fibrosis in patients with overt or occult HBV infection.MethodsWe enrolled all the HBsAg-positive treatment naive patients (overt
Nicola Coppola, Nicola Coppola, Lorenzo Onorato, Marta Panella, Giorgio de Stefano, Nicola Mosca, Carmine Minichini, Vincenzo Messina, Nicoletta Potenza, Mario Starace, Loredana Alessio, Nunzia Farella, Evangelista Sagnelli, Aniello Russo   +13 more
doaj   +1 more source

Integrative characterization of human hepatocellular carcinoma‐derived organoids and their HBV‐associated biology

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
20 HCC‐derived organoids, three adjacent non‐tumour tissue‐derived organoids, and 12 HCC‐derived cell lines from 20 patients were established and biobanked. Integrative analyses combining drug screening, whole‐exome sequencing, and RNA sequencing revealed molecular subtypes and identified candidate determinants of lenvatinib response.
Seo‐Hyeon Kim, YoungRok Choi, Eun Woo Choi, Se Hui Kim, Seung Cheol Oh, Jae Yoon Kim, Su young Hong, Suk Kyun Hong, Kwang‐Woong Lee, Ja‐Lok Ku   +9 more
wiley   +1 more source

Prevalence of occult hepatitis B virus infection in hemodialysis patients in Isfahan, Iran

Advanced Biomedical Research, 2016
Background: The absence of a detectable hepatitis B surface antigen (HBsAg) with or without hepatitis B core antibody (anti-HBc) or hepatitis B surface antibody (anti-HBs) in the presence of hepatitis B virus-DNA (HBV-DNA) is defined as occult HBV ...
Hamid Kalantari, Faezeh Ferdowsi, Majid Yaran   +2 more
doaj   +1 more source

Hepatitis B Virus Infection Status in Japanese Children Prior to Universal Vaccination: Sustained Effectiveness of Mother‐to‐Child Transmission Prevention and Residual Infection Burden

Hepatology Research, Volume 56, Issue 10, Page 1457-1465, October 2026.
ABSTRACT Aim To evaluate the effectiveness of prevention of mother‐to‐child transmission (PMTCT) over 25 years, we conducted a nationwide epidemiological survey through a comprehensive assessment of hepatitis B virus (HBV) markers. Methods Two cohorts were recruited before universal vaccination: children aged 9–10 years undergoing school health ...
Aiko Sakai, Yasuhito Tanaka, Hiroshi Yotsuyanagi, Masaya Sugiyama, Ichiro Morioka, Kiyotaka Kosugiyama, Kimiaki Uetake, Tomohiro Katsuta, Atsushi Imamura, Tomoko Takano, Hitoshi Tajiri, Akihito Ishida, Kosuke Ushijima, Yumiko Nakashima, Hiroyuki Moriuchi, Shinji Iwane, Kota Sawada, Yosuke Shimizu, Yukari Uemura, Manabu Tagawa, Masashi Mizokami, Ryo Sumazaki   +21 more
wiley   +1 more source

"IL28B polymorphism in chronic HBV infection: the CC allele does not correlate with the phase of the infection nor with HBsAg clearance in IFN treated patients". [PDF]

, 2012
IL28B polymorphism (IL28Bp) is associated with spontaneous and treatment induced HCV clearance, whereas its role in HBV infection is still debated. We analysed the correlation between IL28Bp and phase and outcome of HBV infection and HBsAg clearance in ...
CHERUBINI, BEATRICE
core  

Availability of Cancer Screening Across HIV Treatment Sites in the IeDEA Consortium

International Journal of Cancer, Volume 159, Issue 6, Page 1477-1489, 15 September 2026.
In recent years, incorporating comprehensive cancer screening strategies into routine HIV care has gained growing attention. This survey of 220 sites providing HIV care across 41 countries shows that cervical cancer screening has increased in availability over time.
Rachael A. Pellegrino, Bryan E. Shepherd, Sanjay Pujari, Valeria Fink, Gad Murenzi, Miriam Nakalembe, Sally B. Coburn, Eliane Rohner, Antoine Jaquet, Caroline Lade, Brenda Crabtree Ramirez, Kathryn Anastos, Aggrey Semeere, Lesley S. Park, Limpho Mokone, Simon Boni, I Ketut Agus Somia, Emilia M. Jalil, Adebola Adedimeji, Omenge Orang'o, Michael J. Silverberg, Kumbirai Pise Quarter, Eugène Messou, Jeremy Ross, Eduardo Gotuzzo, Patricia Lelo, Helen Byakwaga, Oliver Ezechi, Jonathan Euvrard, Fernanda Maruri, Chad J. Achenbach, Jessica L. Castilho, on behalf of International epidemiology Databases to Evaluate AIDS (IeDEA)   +32 more
wiley   +1 more source

Paraneoplastic Myopathy as a Possible Initial Presentation of Sporadic Burkitt Lymphoma in an Immunocompetent Adult: A Case Report

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Burkitt's lymphoma (BL) is a highly aggressive B‐cell non‐Hodgkin lymphoma with rapid proliferation and early systemic dissemination. Neuromuscular manifestations are rare and are typically secondary to direct infiltration or metabolic complications.
Abolfazl Khalafi‐Nezhad, Dena Firouzabadi, Vahid mohammadkarimi, Amirreza Dehghanian   +3 more
wiley   +1 more source