Diagnosis and Management of Occult Hepatitis B Virus Infection: A Short Review [PDF]
Occult hepatitis B virus infection (OBI) is a challenging clinical entity. It is defined as the presence of viral DNA in the liver or serum of subjects who test negative for the hepatitis B surface antigen.
Agustín Albillos Martínez +3 more
core
Occult hepatitis B in patients on hemodialysis: a review
The hepatitis B virus (HBV) is one of the most frequently transmitted agents in dialysis units. Occult hepatitis B is characterized by HBV infection without detectable surface antigen (HBsAg) in the patient’s serum, a positive or negative HBV DNA marker ...
Andrea M.M. Fontenele, Pharm, MSc. +2 more
doaj +1 more source
Hepatitis B in Organ Transplantation—Current Evidence and Clinical Gaps
ABSTRACT Over the past several decades there have been significant advances in nucleos(t)ide analogue (NA) antiviral therapy for hepatitis B virus (HBV) and global expansion of primary prevention through immunization. Despite this, HBV remains a leading cause of chronic liver disease globally, affecting over 250 million people.
Oscar A. Fernandez‐Garcia +3 more
wiley +1 more source
Hepatitis B virus in silvery gibbons (Hylobates moloch) [PDF]
This research investigated a number of issues regarding hepatitis B virus (HBV) in the silvery gibbon (Hylobates moloch). Due to the relatively recent discovery of the virus in nonhuman primate populations, specific knowledge of the biological behaviour ...
Payne, Karen Louise
core
Geographic and species association of hepatitis B virus genotypes in non-human primates [PDF]
Infection with hepatitis B virus (HBV) has been detected in human populations throughout the world, as well as in a number of ape species (Pan troglodytes, Gorilla gorilla, gibbons [Nomascus and Hylobates species] and Pongo pygmaeus).
Holmes, E.C +8 more
core +1 more source
Abstract Background Blood donor screening occasionally identifies individuals with high HBV surface antigen (HBsAg) levels despite undetectable or extremely low HBV DNA. Molecular basis and transfusion risk of this discordant profile remain unclear. Study Design and Methods Seventy‐five blood donors with HBsAg >100 IU/mL and undetectable or very low ...
Maelenn Païline Delcourt +8 more
wiley +1 more source
PREVALENCE OF OCCULT HEPATITIS B INFECTION IN IRANIAN CANCER PATIENTS BEFORE CHEMOTHERAPY TREATMENT
Background Occult hepatitis B infection is characterized by negative hepatitis B surface antigen (HBsAg) and also detectable hepatitis B virus (HBV) -DNA, with or without hepatitis B core antibody (anti-HBc).
Mahmud BAGHBANIAN +5 more
doaj +1 more source
Primary seronegative but molecularly evident hepadnaviral infection engages liver and induces hepatocarcinoma in the woodchuck model of hepatitis B. [PDF]
Hepadnavirus at very low doses establishes in woodchucks asymptomatic, serologically undetectable but molecularly evident persistent infection. This primary occult infection (POI) preferentially engages the immune system and initiates virus-specific T ...
Patricia M Mulrooney-Cousins +3 more
doaj +1 more source
20 HCC‐derived organoids, three adjacent non‐tumour tissue‐derived organoids, and 12 HCC‐derived cell lines from 20 patients were established and biobanked. Integrative analyses combining drug screening, whole‐exome sequencing, and RNA sequencing revealed molecular subtypes and identified candidate determinants of lenvatinib response.
Seo‐Hyeon Kim +9 more
wiley +1 more source
A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers [PDF]
Background and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV ...
Stefan Zeuzem +15 more
core +2 more sources

