Results 91 to 100 of about 1,649,829 (251)
, 2007 A number of risk factors appear to play a role in Hepatocellularcinoma (HCC), HBV infection being one of the most important. Chronic inflammation and cytokines are key determinants in the development of fibrosis and liver cell proliferation.
Chemin, Isabelle
core +1 more source
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source
Occult hepatitis B virus infection in association with asthma bronchiale [PDF]
, 2011 Clinica Medicală №4 – DisciplinaGastroenterologieOccult HBV infection is a clinical entity characterised by the detection or the absence of HBV-DNA in serum and/or the detection of HBV-DNA in liver without appreciation of hepatitis B surface antigen ...
Chirvas, Elena
core +1 more source
Cost-effectiveness of screening for colorectal cancer with once-only flexible sigmoidoscopy and faecal occult blood test [PDF]
On the basis of a randomized controlled trial we estimate the cost per life-year gained for six different strategies for colorectal cancer screening. Individuals in the age group 50 to 64 years were randomly selected for either flexible sigmoidoscopy or ...
Aas, Eline
core
Advanced Science, EarlyView.The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu +4 more
wiley +1 more source
Advanced Science, EarlyView.An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin +18 more
wiley +1 more source
Occult Infection with Hepatitis C Virus: Looking for Clear-Cut Boundaries and Methodological Consensus. [PDF]
J Clin Med, 2021 Wróblewska A, Bielawski KP, Sikorska K.
europepmc +1 more source
Advanced Science, EarlyView.By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu +11 more
wiley +1 more source
Endemic HBV among hospital in-patients in Bangladesh, including evidence of occult infection. [PDF]
J Gen Virol, 2021 Chowdhury FR +18 more
europepmc +1 more source
SAT1‐Induced Spermidine Depletion Potentiates Food Allergy
Advanced Science, EarlyView.Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu +8 more
wiley +1 more source