Results 201 to 210 of about 2,013 (259)

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Simultaneous Pi2 pulsation detected by CSES-01, Swarm, RBSP and Arase satellites. [PDF]

Sci Rep
Ghamry E, Yamamoto K, Marchetti D, Takahashi K, Hawash I, Khalifa M, Bulusu J, Metwaly M, Miyoshi Y, Zhima Z, Matsuoka A, Teramoto M, Kasahara Y, Tsuchiya F, Kumamoto A, Shinbori A, Shinohara I.   +16 more
europepmc   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

Arthritis &Rheumatology, Accepted Article.
Background Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. Immunoglobulin G (IgG) from LN patients displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay, Alexia Orellana, George C. Tsokos, Rhea Bhargava   +3 more
wiley   +1 more source

A data-to-forecast machine learning system for global weather. [PDF]

Nat Commun
Sun X, Zhong X, Xu X, Huang Y, Li H, Neelin JD, Chen D, Feng J, Han W, Wu L, Qi Y.   +10 more
europepmc   +1 more source

Discovery of H 3 + and infrared aurorae at Neptune with JWST. [PDF]

Nat Astron
Melin H, Moore L, Fletcher LN, Hammel HB, O'Donoghue J, Stallard TS, Milam SN, Roman M, King ORT, Rowe-Gurney N, Thomas EE, Wang R, Tiranti PI, Harkett J, Knowles KL.   +14 more
europepmc   +1 more source

The January 2022 Hunga eruption cooled the southern hemisphere in 2022 and 2023. [PDF]

Commun Earth Environ
Gupta AK, Mittal T, Fauria KE, Bennartz R, Kok JF.   +4 more
europepmc   +1 more source

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OCCULT MACULOPATHY

RETINAL Cases & Brief Reports, 2012
To report a case of bilateral decrease in central vision with almost normal fundus examination.A 50-year-old white man with central visual loss followed since 2006 with detailed ophthalmologic examinations and ancillary tests, including autoimmune and antiretinal antibody analyses.Virtually normal ophthalmoscopic examination, fluorescein and ...
Nandini, Menon, Lee M, Jampol
openaire   +2 more sources