Results 261 to 270 of about 145,824 (331)

Millefeuille: The layering of the Martian atmosphere observed in forward scattering geometry. [PDF]

Sci Adv
Thomas N, Almeida M, Mokhtari O, Pommerol A, Read M, Geiger B, Riu L, Patel MR, Byrne S, Sutton S.   +9 more
europepmc   +1 more source

Tropical Cold-Point Tropopause: Climatology, Seasonal Cycle, and Intraseasonal Variability Derived from COSMIC GPS Radio Occultation Measurements

, 2012
Joowan Kim, S. Son
semanticscholar   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Saturn's F ring is intermittently shepherded by Prometheus. [PDF]

Sci Adv
Cuzzi JN, Marouf EA, French RG, Murray CD, Cooper NJ.   +4 more
europepmc   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Spectroscopic insights into the near-earth didymos-dimorphos binary system following the double asteroid redirection test (DART) mission impact. [PDF]

Nat Commun
Lazzarin M, La Forgia F, Farina A, Migliorini A, Frattin E, Ochner P, Michel P, Kueppers M, de Leon J, Carnelli I, Ulamec S, Chabot N, Ammannito E, Amoroso M, Geier S, Hirabayashi M, Kareta T, Li JY, Mura AC, Oszkiewicz D, Popescu M, Rivkin AS.   +21 more
europepmc   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

A new method for correcting the refraction angle of starlight under the conditions of 0-[Formula: see text] zenith distance and 0-200 km observation height. [PDF]

Sci Rep
Yu D, Wang Y, Huang Z, Liu X.
europepmc   +1 more source

Radio Occultation Investigation of the Rings of Saturn and Uranus

, 1997
E. A. Marouf
openalex   +1 more source